林乐涛,邹英华.肝癌肿瘤微环境中非癌细胞成分的研究进展与介入治疗展望[J].中国介入影像与治疗学,2017,14(6):378-381
肝癌肿瘤微环境中非癌细胞成分的研究进展与介入治疗展望
Research progresses on non-cancer-cell component of tumor microenvironment in hepatocellular carcinoma and prospect of interventional therapy
投稿时间:2017-02-02  修订日期:2017-03-26
DOI:10.13929/j.1672-8475.201702022
中文关键词:  肿瘤微环境  外泌体  趋化因子  局部条件  介入治疗
英文关键词:Tumor microenvironment  Exosome  Chemokine  Local condition  Interventional therapy
基金项目:
作者单位E-mail
林乐涛 北京大学第一医院介入血管外科, 北京 100034  
邹英华 北京大学第一医院介入血管外科, 北京 100034 yinghzou@139.com 
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中文摘要:
      肝癌肿瘤微环境中的非癌细胞成分,因其基因组的相对稳定性而受到关注。本文从肿瘤微环境的组成及其特点、肝癌肿瘤微环境的组成出发,对肝癌肿瘤微环境中非癌细胞成分的3个研究新的热点(外泌体、趋化因子及无生物活性条件的局部调节)进行综述,并对其在介入治疗方面的应用进行展望。
英文摘要:
      The non-cancer-cell component of the tumor microenvironment in hepatocellular carcinoma (HCC) has drawn the attention of the researchers because of its relative stability of the genome. The composition and characteristics of the tumor microenvironment and the composition of the tumor microenvironment in hepatocellular carcinoma were introduced in this article. Besides, the recent studies about the non-cancer-cell component of the tumor microenvironment in HCC were reviewed from three aspects:The exosomes, the chemokines and the local conditions without biological activity. The application of non-cancer-cell in interventional treatment in the future was also discussed.
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