鲁仁财,赵卫,易根发,姚瑞红,张淮.不同T2WI信号子宫肌瘤超声造影分析[J].中国介入影像与治疗学,2017,14(8):489-493
不同T2WI信号子宫肌瘤超声造影分析
Parametric imaging of contrast-enhanced ultrasound of uterine fibroids with different T2WI signal intensity
投稿时间:2017-02-08  修订日期:2017-05-26
DOI:10.13929/j.1672-8475.201702007
中文关键词:  子宫肌瘤  高强度聚焦超声  动态血管模型  磁共振成像
英文关键词:Uterine fibroids  High intensity focused ultrasound  Dynamic vascular pattern  Magnetic resonance imaging
基金项目:
作者单位E-mail
鲁仁财 昆明医科大学第一附属医院医学影像科, 云南 昆明 650032  
赵卫 昆明医科大学第一附属医院医学影像科, 云南 昆明 650032 kyyyzhaowei@vip.km169.net 
易根发 昆明医科大学第一附属医院医学影像科, 云南 昆明 650032  
姚瑞红 昆明医科大学第一附属医院医学影像科, 云南 昆明 650032  
张淮 昆明医科大学第一附属医院医学影像科, 云南 昆明 650032  
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中文摘要:
      目的 对行高强度聚焦超声(HIFU)消融治疗的不同T2信号的子宫肌瘤行CEUS定量分析及动态血管模型(DVP)参数成像。方法 对16例行HIFU治疗的单发子宫肌瘤患者,依据术前MRI T2WI信号不同分为高信号组(n=6)、等信号组(n=4)、低信号组(n=6),于HIFU治疗前行CEUS并利用SonoLiver CAP软件对其行定量分析,以子宫肌瘤与周围肌层增强水平差值为参数行DVP参数成像构建。结果 3组峰值强度、上升时间、达峰时间、平均渡越时间分别为:高信号组为(235.40±35.46)%、(22.80±3.16) s、(25.09±2.44) s、(125.78±27.63) s,等信号组为(71.97±2.43)%、(24.85±3.22) s、(32.81±3.92) s、(66.52±3.48) s,低信号组为(16.17±2.83)%、(25.42±2.66) s、(32.82±3.76) s、(64.27±3.33) s,3组间各参数比较差异均有统计学意义(P均<0.05)。高信号、低信号组子宫肌瘤的DVP曲线主要表现为未消退型和负向型。结论 CEUS参数成像分析和DVP参数图可直观、动态、定量地反映不同T2信号子宫肌瘤的血流灌注差异,为HIFU治疗子宫肌瘤提供重要信息。
英文摘要:
      Objective To investigate the value of parametric imaging of CEUS in uterine fibroids with different signal intensity on T2WI by high intensity focused ultrasound (HIFU), and dynamic vascular pattern (DVP). Methods Totally 16 patients with single uterine fibroids were divided into high intensity group (n=6), isointensity group (n=4) and low intensity group (n=6) according the signal intensity on T2WI before HIFU treatment. CEUS were performed on each patient. SonoLive CAP software was used to analyze the CEUS images and DVP parametric images were reconstructed. Results The maximum intensity, rising time, time to peak and mean transit time were (235.40±35.46)%, (22.80±3.16)s, (25.09±2.44)s, (125.78±27.63)s in high intensity group, (71.97±2.43)%, (24.85±3.22)s, (32.81±3.92)s, (66.52±3.48)s in isointensity group and (16.17±2.83)%, (25.42±2.66)s, (32.82±3.76)s, (64.27±3.33)s in low intensity group. There were statistically significant differences among three groups (all P<0.05). DVP curve was divided into two types:non-washout in high intensity group and cystic type in low intensity group. Conclusion CEUS and DVP imaging can directly quantitively display the difference of blood perfusion among the uterine fibroids with different signal intensity on T2WI which can provide important information for HIFU treatment in uterine fibroids.
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