丛瑞,李晶.感兴趣区大小对剪切波弹性成像诊断乳腺肿块的影响[J].中国介入影像与治疗学,2017,14(9):534-538
感兴趣区大小对剪切波弹性成像诊断乳腺肿块的影响
Influence of region of interest size on performance of shear wave elastography in breast masses
投稿时间:2017-02-10  修订日期:2017-08-02
DOI:10.13929/j.1003-3289.201702010
中文关键词:  超声检查  剪切波弹性成像  乳腺肿瘤  感兴趣区
英文关键词:Ultrasonography  Shear wave elastography  Breast neoplasms  Region of interest
基金项目:
作者单位E-mail
丛瑞 中国医科大学附属盛京医院超声科, 辽宁 沈阳 110004  
李晶 中国医科大学附属盛京医院超声科, 辽宁 沈阳 110004 lijing@sj-hospital.org 
摘要点击次数: 1634
全文下载次数: 977
中文摘要:
      目的 探讨不同大小ROI对剪切波弹性成像(SWE)鉴别诊断乳腺良恶性肿块的影响。方法 对因乳腺实性肿块接受手术治疗的乳腺患者225例(共239个肿块)进行SWE,采用"较大ROI"和"ROI=2 mm"两种方法测量SWE弹性定量参数,包括弹性最大值(Emax)、弹性平均值(Emean)、弹性标准差(SD)及弹性比(Eratio),采用ROC曲线比较两种方法下各参数诊断效能的差异,获得最佳临界值、敏感度及特异度。结果 两种ROI下获得的Eratio诊断乳腺恶性肿瘤的AUC差异有统计学意义(P=0.046),两种ROI测得Emax、Emean及SD诊断乳腺恶性肿瘤的AUC差异无统计学意义(P均>0.05)。"较大ROI"时Emax、Emean的特异度较高,而"ROI=2 mm"时SD及Eratio的特异度较高,差异均有统计学意义(P均<0.05)。两种方法获得的SWE参数与BI-RADS分别联合后的诊断乳腺恶性肿瘤的AUC差异无统计学意义(P均>0.05)。结论 不同大小ROI仅可影响Eratio诊断乳腺恶性肿瘤的效能,而对SWE定量参数(Emax、Emean、SD)及其与BI-RADS联合后的诊断效能无显著性影响。
英文摘要:
      Objective To explore the influence of ROI size on the diagnostic performance of shear wave elstography (SWE) of breast masses.Methods A total of 225 consecutive patients with 239 solid breast masses underwent SWE before surgery, and then quantitative SWE parameters, including the maximum stiffness (Emax), mean stiffness (Emean), ratio of stiffness of the mass to stiffness of surrounding fat (Eratio) and standard deviation (SD), were measured by two methods, one method was using "larger ROI" to include the largest part of a mass, and the other was placing fixed "ROI=2 mm" over the stiffest part of the lesion to measure. The diagnostic performance of the two methods were evaluated by ROC curve, and the cut-off value, sensitivity and specificity of each SWE parameter were obtained.Results There were no statistically significant differences between the performance of Emax, Emean and SD from the two different methods (all P>0.05), the performance of Eratio of the two methods showed significant difference (P=0.046). The significantly higher specificity of Emax and Emean in the "larger ROI" were found, and the significantly higher sensitivity of SD and Eratio in the "ROI=2 mm" was found. Furthermore, the diagnostic performance of combination of SWE and BI-RADS were not greatly affected by the ROI size, the difference had no statistical significance (all P>0.05).Conclusion The ROI size only affects the diagnostic performance of Eratio, and donot affect the diagnostic performance of the quantitative SWE parameters (Emax, Emean, SD) and combination of SWE and BI-RADS.
查看全文  查看/发表评论  下载PDF阅读器
关闭