| 林淑芝,徐倩,武金玉,严昆,吴薇.超声引导下经皮射频消融治疗恶性肿瘤肝转移[J].中国介入影像与治疗学,2018,15(1):29-32 |
| 超声引导下经皮射频消融治疗恶性肿瘤肝转移 |
| Ultrasound-guided percutaneous radiofrequency ablation in treatment of liver metastases of malignant tumor |
| 投稿时间：2017-08-02 修订日期：2017-12-12 |
| DOI：10.13929/j.1672-8475.201708002 |
| 中文关键词: 超声检查 导管消融术 肝 肿瘤转移 |
| 英文关键词:Ultrasonography Catheter ablation Liver Neoplasm metastasis |
| 基金项目:哈尔滨市自然科学基金（2009RFQQS019）。 |
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| 中文摘要: |
| 目的 探讨超声引导下经皮射频消融（RFA）治疗恶性肿瘤肝转移的应用价值。方法 回顾性分析2009年12月-2015年5月于我院接受超声引导下经皮RFA治疗的109例恶性肿瘤肝转移患者的临床及影像学资料。结果 109例肝转移癌患者中，单发31例（31/109，28.44%），多发78例（78/109，71.56%）；肝转移病灶来源于结直肠、肺、乳腺、胃、胰腺、卵巢及前列腺的恶性肿瘤。共198个肝转移癌病灶中，直径<3 cm者151个（151/198，76.26%），直径≥ 3 cm者47个（47/198，23.74%）。治疗后1个月，187个（187/198，94.44%）病灶完全灭活，11个（11/198，5.56%）病灶存在残余活性。与治疗前比较，治疗后1个月患者肿瘤标志物指标明显改善（P均<0.05）。术中及术后并发症发生率6.42%（7/109）。结论 对于非手术适应证恶性肿瘤肝转移患者，超声引导下经皮RFA治疗相对安全、有效，短期内可局部控制肝内转移癌的活性。 |
| 英文摘要: |
| Objective To investigate the application value of ultrasound-guided percutaneous radiofrequency ablation (RFA) in treatment of liver metastases of malignant tumor. Methods Clinical and imaging data of 109 patients with liver metastases of malignant tumor who underwent ultrasound-guided percutaneous RFA during December 2009 to May 2015 were retrospectively analyzed. Results There were 31 patients (31/109, 28.44%) with single liver metastases and 78 patients (78/109, 71.56%) with multiple lesions. The primary tumors included colorectal, lung, breast, gastric, pancreatic, ovarian and prostate carcinomas. Among all 198 liver metastases, there were 151 (151/198, 76.26%) with diameter <3 cm and 47 (47/198, 23.74%) with diameter ≥ 3 cm. One month after RFA, 187 lesions (187/198, 94.44%) were completely inactivated, while the other 11 lesions (11/198, 5.56%) still had residual activity. One month later, the tumor markers improved obviously compared with those before treatment (all P<0.05). The incidence of intraoperative and postoperative complications was 6.42% (7/109). Conclusion Ultrasound-guided percutaneous RFA is a safe and effective treatment for patients with non-surgical indications of malignant liver metastases, which can partially control the survival activity of liver metastases. |
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