| 李运江,周坦洋,张岳林,王薇薇,孙军辉.不同粒径Embosphere栓塞微球在部分脾动脉栓塞术中的应用[J].中国介入影像与治疗学,2018,15(7):401-404 |
| 不同粒径Embosphere栓塞微球在部分脾动脉栓塞术中的应用 |
| Application of different size Embosphere microspheres in partial splenic artery embolism |
| 投稿时间：2017-11-28 修订日期：2018-04-25 |
| DOI：10.13929/j.1672-8475.201711053 |
| 中文关键词: 脾动脉 栓塞 微球 |
| 英文关键词:Splenic artery Embolism Microsphere |
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| 中文摘要: |
| 目的 探讨采用不同粒径Embosphere栓塞微球对肝硬化脾功能亢进患者行部分性脾动脉栓塞术（PSE）的安全性和有效性。方法 回顾性分析因肝硬化脾功能亢进接受PSE治疗的40例患者，PSE中使用直径为300~500 μm、500~700 μm Embosphere栓塞微球者各20例，分别归入A组和B组，观察2组患者术前和术后第3天、第7天、1个月、3个月外周血白细胞、血小板计数变化及术后发热和疼痛的情况。结果 PSE后2组患者血小板及白细胞计数均较PSE前有明显升高（P均<0.05）。A组术后发热及疼痛的发生率及程度明显轻于B组（P均<0.05）。结论 作为PSE栓塞材料，直径300~500 μm的Embosphere微球更为安全、可靠。 |
| 英文摘要: |
| Objective To explore the safety and efficacy of Embosphere microspheres with different particle diameters in partial splenic artery embolism (PSE) for treatment of hypersplenism secondary to liver cirrhosis. Methods Forty patients underwent PSE for treatment of hypersplenism secondary to liver cirrhosis were retrospectively analyzed, including 20 embolized with microspheres diameters of 300-500 μm (group A) and 20 with microspheres diameters of 500-700 μm (group B). The changes of white blood cells, platelet count and postoperative pain and fever were followed up on the 3rd day, the 7th day, the 1st month and the 3rd month after PSE and compared between the two groups. Results The counts of white cells and platelet after PSE were all significantly higher than those before PSE (all P<0.05). The occurence rate, degree of pain and fever of group A were all less than those of group B (all P<0.05). Conclusion Embosphere embolization microspheres with diameters of 300-500 μm are safe and reliable embolic materials in PSE for treatment of hypersplenism secondary to liver cirrhosis. |
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