| 李宏伟,蒋小凤,张川,李兵,徐晓雪,杨汉丰,杜勇,卓丽华.对比CT引导微波消融与冷冻消融治疗肺恶性肿瘤[J].中国介入影像与治疗学,2019,16(2):83-87 |
| 对比CT引导微波消融与冷冻消融治疗肺恶性肿瘤 |
| Comparison between CT-guided microwave ablation and cryoablation in treatment of malignant pulmonary tumors |
| 投稿时间：2018-05-03 修订日期：2018-12-20 |
| DOI：10.13929/j.1672-8475.201805001 |
| 中文关键词: 肺肿瘤 微波消融 冷冻消融 |
| 英文关键词:lung neoplasms microwave ablation cryoablation |
| 基金项目:南充市市校科技战略合作专项项目（NSMC20170301）。 |
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| 中文摘要: |
| 目的 对比CT引导微波消融与冷冻消融治疗肺部恶性肿瘤的有效性及安全性。方法 回顾性分析48例接受CT引导下消融治疗的原发或转移性肺部恶性肿瘤患者的临床及随访资料；其中微波消融组29例，冷冻消融组19例，比较2组间术后并发症发生率、消融治疗有效率、疾病控制率及患者生存率的差异。结果 微波消融组与冷冻消融组间术后并发症发生率差异无统计学意义[34.48%（10/29）vs 42.11%（8/19）；χ2=0.285，P=0.594]，术后3个月消融治疗有效率[72.41%%（21/29）vs 73.68%（14/19）；χ2=0.009，P=0.923]及疾病控制率[96.55%（28/29）vs 94.74%（18/19）；χ2=0.095，P=0.758]差异均无统计学意义。微波消融组患者术后6、12、24、36个月生存率分别为92.72%、81.28%、64.54%、54.91%，冷冻消融组分别为94.07%、81.13%、57.33%、43.04%，2组患者术后生存率差异无统计学意义（P=0.793）。结论 CT引导微波消融与冷冻消融治疗肺部恶性肿瘤均较为有效且相对安全。 |
| 英文摘要: |
| Objective To compare the efficacy and safety of microwave ablation and cryoablation in treatment of malignant pulmonary tumors. Methods A retrospective analysis was performed on 48 patients with primary or metastatic pulmonary malignant tumors who underwent CT-guided ablation, among them 29 were treated with microwave ablation (microwave ablation group) and another 19 received cryablation (cryablation group). Statistical analysis was used to compare the incidence of postoperative complications, the rate of effectiveness ablation, the rate of disease control and the survival rate between the two groups. Results There was no statistical difference of the incidence of postoperative complications between microwave ablation group and cryoablation group (34.48%[10/29] vs 42.11%[8/19]; χ2=0.285, P=0.594). No statistical difference of the rate of effectiveness ablation (72.41%%[21/29] vs 73.68%[14/19]; χ2=0.009, P=0.923) nor the rate of disease control (96.55%[28/29] vs 94.74%[18/19]; χ2=0.095, P=0.758) was found 3 months after ablation. The survival rate at 6, 12, 24 and 36 months after treatment was 92.72%, 81.28%, 64.54% and 54.91% in microwave ablation group, and 94.07%, 81.13%, 57.33% and 43.04% in cryablation group, respectively. There was no statistical difference of survival rate between the two groups (P=0.793). Conclusion CT-guided microwave ablation and cryoablation are both effective and relatively safe for treatment of malignant pulmonary tumors. |
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