张肖,张晶,张啸波,何晓锋,张欣,魏颖恬,李竞,肖越勇.CT引导下射频消融术治疗肺转移瘤[J].中国介入影像与治疗学,2019,16(3):131-134
CT引导下射频消融术治疗肺转移瘤
CT-guided radiofrequency ablation in treatment of lung metastatic tumors
投稿时间:2018-08-13  修订日期:2018-11-22
DOI:10.13929/j.1672-8475.201808014
中文关键词:    肿瘤转移  体层摄影术,X线计算机  导管消融术
英文关键词:lung  neoplasm metastasis  tomography,X-ray computed  catheter ablation
基金项目:北京市科技新星计划(Z181100006218026)。
作者单位E-mail
张肖 中国人民解放军总医院放射诊断科, 北京 100853  
张晶 中国人民解放军总医院放射诊断科, 北京 100853  
张啸波 中国人民解放军总医院放射诊断科, 北京 100853  
何晓锋 中国人民解放军总医院放射诊断科, 北京 100853  
张欣 中国人民解放军总医院放射诊断科, 北京 100853  
魏颖恬 中国人民解放军总医院放射诊断科, 北京 100853  
李竞 中国人民解放军总医院放射诊断科, 北京 100853  
肖越勇 中国人民解放军总医院放射诊断科, 北京 100853 xiaoyueyong@vip.sina.com 
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中文摘要:
      目的 探讨CT引导下射频消融术(RFA)治疗肺转移瘤的应用价值。方法 对102例患者128个肺部转移性病灶行CT引导下RFA,消融功率范围40~80 W,消融时间12~25 min;术后以CT随访评估疗效。结果 对所有患者均成功实施RFA。治疗后完全消融病灶120个,CT复查显示病灶无强化,边缘清晰,体积呈不同程度渐进性缩小,呈纤维条索状、结节状、空洞状等改变。术后3个月复查8个病灶可见边缘结节状强化,即刻行2次RFA消融术,术后复查其中7个病灶完全灭活,1个仍有增大趋势,行放射性粒子植入术控制病灶。术后6例出现中、大量气胸,予以胸腔闭式引流;少量气胸12例,发热12例,对症处理后均好转;无严重并发症发生。结论 CT引导下经皮穿刺RFA治疗肺转移瘤安全、有效,具有高度临床应用价值。
英文摘要:
      Objective To observe the value of CT guided radiofrequency ablation (RFA) in treatment of lung metastases. Methods Totally 128 lung metastatic lesions in 102 patients were treated with CT-guided RFA. The ablation power range was 40-80 W, the ablation time was 12-25 min, and the effect was evaluated using follow-up CT images. Results All operations were carried out successfully. A total of 120 lesions were completely ablated. CT following-up showed the lesions with no enhancement, with clear edges, the volumes gradually reduced in different degrees, while fiber strips, nodules and hollows could be observed. Nodular enhancement on the margins were observed in 8 lesions in follow-up CT images 3 months later, and RFA was performed again. Complete ablation was achieved in 7 of those 8 lesions, while 1 lesion kept increase, and the patient underwent radioactive particle implantation. After operation, media and massive pneumothorax occurred in 6 patients who underwent thoracic close drainage, while slight pneumothorax and fever were noticed each in 12 patients and released after symptomatic treatment. No serious complication occurred. Conclusion CT-guided percutaneous radiofrequency ablation is safe and effective in treatment of pulmonary metastasis, therefore having high application value.
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