| 李艳,程勇,冯茜茜,沈倩,兰永树.扫描及重建参数对肺磨玻璃结节体积测量影响的体模研究[J].中国介入影像与治疗学,2019,16(11):691-695 |
| 扫描及重建参数对肺磨玻璃结节体积测量影响的体模研究 |
| Impact of scanning and reconstruction parameters on volume measurement of pulmonary ground glass nodules for phantom study |
| 投稿时间：2019-05-31 修订日期：2019-09-20 |
| DOI：10.13929/j.1672-8475.201905050 |
| 中文关键词: 肺肿瘤 体层摄影术,X线计算机 体模,显像术 |
| 英文关键词:lung neoplasms tomography, X-ray computed phantoms, imaging |
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| 摘要点击次数: 2047 |
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| 中文摘要: |
| 目的 探讨MSCT扫描与重建参数对仿真人体体模肺磨玻璃结节容积测量的影响。方法 采用GE VCT对8个肺磨玻璃结节进行不同管电压（80 kV、100 kV、120 kV）、管电流（100 mA、150 mA、200 mA）扫描，并对80 kV、150 mA组原始数据行不同层厚（0.625 mm、1.250 mm）、不同重建算法（soft、standard、lung、bone）、不同重建野（36 cm、18 cm）重建。由2名胸部放射诊断医师分别用软件对磨玻璃结节进行容积测量，并对绝对错误率（APE）=（|V测量-V实际|）/V实际×100%进行统计学分析。采用组内相关系数（ICC）评估2名医师体积测量结果的一致性。结果 2名医师对肺磨玻璃结节体积测量的ICC=0.98。不同管电压条件下各结节的APE值差异无统计学意义（P>0.05），而管电流为150 mA，APE值最小（P<0.05）。结节的APE值在2种层厚之间差异无统计学意义（P>0.05）。随着重建野缩小，APE值减小（P<0.05）。不同重建算法对结节的APE值影响不同，差异有统计学意义（P<0.05），lung算法时APE值较小。低密度小结节（CT值为-800 HU，直径5 mm）在各种条件下的APE值均大于10。结论 MSCT采用80 kV、150 mA扫描结合靶重建、肺算法可一定程度减小辐射剂量并且提高磨玻璃结节容积测量的准确性。低密度小结节不适合用肺结节分析软件分析。 |
| 英文摘要: |
| Objective To explore the effect of MSCT scanning and reconstruction parameters on volume measurement of phantom pulmonary ground glass nodules. Methods Eight pulmonary ground glass nodules were scanned by different tube voltages (80 kV, 100 kV, 120 kV), tube currents (100 mA, 150 mA, 200 mA) by GE VCT. The original data in 150 mA, 80 kV group were reconstructed with different slice thickness (0.625 mm, 1.25 mm), reconstruction algorithm (soft, standard, lung, bone) and field of view (36 cm, 18 cm). The two independent chest radiologists measured the volume of ground glass nodules by lung nodule assessment software. The absolute percentage error (APE)=(|Vmeasurement-Vactual|)/Vactual×100% was analyzed statisticall. The consistency of volume measurements was evaluated by intraclass correlation coefficient (ICC). Results There was great agreement of inter-observers in volume measurement of phantom pulmonary ground glass nodules (ICC=0.98). There was no significant difference in APE value among the nodules under different tube voltages (P>0.05), while the tube current was 150 mA and the APE value was the lowest (P<0.05). There was no significant difference in APE value under slice thickness (P>0.05). As the reconstructed field decreased, the APE value decreased (P<0.05). Different reconstruction algorithms had different effects on the APE value of nodules (P<0.05). The APE value in lung algorithm was smaller than that in the other algorithms. The APE values of low density and small nodules (CT value=-800 HU, diameter=5 mm) were higher than 10 under various conditions. Conclusion 80 kV, 150 mA of scanning parameters combined with target reconstruction and lung algorithm can reduce the radiation dose and improve the accuracy of volume measurement of ground glass nodules in MSCT, and the pulmonary nodule analysis software is not suitable for the analysis of small ground glass nodules of lung. |
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