| 李莹莹,傅璠,刘元波,季楠,汪晓鹏,孙胜军.MRI强化程度鉴别诊断小脑囊实性血管母细胞瘤与毛细胞星形细胞瘤[J].中国介入影像与治疗学,2020,17(1):31-34 |
| MRI强化程度鉴别诊断小脑囊实性血管母细胞瘤与毛细胞星形细胞瘤 |
| Differential diagnosis of cerebellum cystic-solid hemangioblastoma and pilocytic astrocytoma according to MRI enhancement degree |
| 投稿时间：2019-08-05 修订日期：2019-11-13 |
| DOI：10.13929/j.issn.1672-8475.2020.01.010 |
| 中文关键词: 血管母细胞瘤 星形细胞瘤 小脑 磁共振成像 |
| 英文关键词:hemangioblastoma astrocytoma cerebellum magnetic resonance imaging |
| 基金项目:首都卫生发展科研专项（2018-2-1074）。 |
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| 中文摘要: |
| 目的 探讨MRI强化程度对鉴别诊断小脑囊实性血管母细胞瘤与毛细胞星形细胞瘤的价值。方法 回顾性分析经手术病理证实的30例小脑囊实性血管母细胞瘤及30例毛细胞星形细胞瘤患者的MRI资料，检测病灶实性成分强化程度值，绘制ROC曲线，评价实性成分强化程度值对鉴别诊断二者的效能。结果 血管母细胞瘤中，15例为囊腔结节型、15例为实性肿块伴囊变型，实质部分均明显均匀强化；毛细胞星形细胞瘤中，11例为囊腔结节型、19例为实性肿块伴囊变型，21例实质部分均匀强化、9例不均匀强化。血管母细胞瘤实质部分强化程度值为4.20（3.28，4.84），毛细胞星形细胞瘤为1.95（1.49，2.43）（F=72.69，P<0.01）。以实性成分强化幅度值2.58为阈值，诊断小脑囊实性血管母细胞瘤的特异度和敏感度分别为88.9%和92.9%，AUC为0.95。结论 肿瘤实性成分MRI强化程度有助于鉴别小脑囊实性血管母细胞瘤与毛细胞星形细胞瘤。 |
| 英文摘要: |
| Objective To investigate the value of MRI enhancement degree in differential diagnosis of cerebellum cystic-solid hemangioblastoma and pilocytic astrocytoma. Methods MRI data of 30 patients with cerebellum cystic-solid hemangioblastoma and 30 patients with cerebellum cystic-solid pilocytic astrocytoma confirmed by operation and pathology were retrospectively analyzed. The enhancement value of the solid component of the lesion was calculated, then ROC curve was drawn, and the diagnostic effect of the solid component enhancement level was evaluated. Results Among 30 cases of cerebellum cystic-solid hemangioblastoma, cystic nodules were in 15 cases, while solid masses with cystic changes were observed in other 15 cases, and the parenchyma part was uniformly strengthened. Among 30 cases of cerebellum cystic-solid pilocytic astrocytoma, cystic nodules were detected in 11 cases, where as solid masses with cystic changes were noticed in 19 cases, 21 cases had uniform enhancement of parenchyma and 9 cases showeduneven enhancement. The parenchyma enhancement degree of cerebellum cystic-solid hemangioblastoma was 4.20 (3.28,4.84), of cerebellum cystic-solid pilocytic astrocytoma was 1.95 (1.49,2.43) (F=72.69,P<0.01). The specificity and sensitivity of diagnosis of cerebellum cystic-solid hemangioblastoma was 88.9% and 92.9%, respectively. Taken the enhancement amplitude 2.58 as the threshold, the AUC was 0.95. Conclusion The degree of MRI enhancement of solid tumor components is helpful to distinguishing cerebellum cystic-solid hemangioblastoma and pilocytic astrocytoma. |
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