袁晨,瞿小峰,邓小文,李波,刘一之.血流彩色编码成像技术评估颈动脉植入支架前后血流动力学变化[J].中国介入影像与治疗学,2020,17(5):266-269
血流彩色编码成像技术评估颈动脉植入支架前后血流动力学变化
Color coding of digital subtraction angiography in assessment of hemodynamic changes before and after carotid stent implantation
投稿时间:2019-11-11  修订日期:2020-04-09
DOI:10.13929/j.issn.1672-8475.2020.05.003
中文关键词:  支架  颈动脉  介入治疗  血管造影术,数字减影
英文关键词:stents  carotid arteries  interventional therapy  angiography, digital subtraction
基金项目:
作者单位E-mail
袁晨 苏州大学附属第一医院介入科, 江苏 苏州 215000  
瞿小峰 苏州大学附属第一医院介入科, 江苏 苏州 215000  
邓小文 苏州大学附属第一医院介入科, 江苏 苏州 215000  
李波 苏州大学附属第一医院介入科, 江苏 苏州 215000  
刘一之 苏州大学附属第一医院介入科, 江苏 苏州 215000 liuyz-sz@163.com 
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中文摘要:
      目的 探讨彩色血流编码DSA(CC-DSA)评估颈动脉支架植入术(CAS)前后血流动力学变化的可行性。方法 回顾性分析接受CAS治疗的颈内动脉起始段重度狭窄患者16例。将CAS前后颈动脉造影图像经CC-DSA后处理得到相应的彩色血流编码图像,分别于颈总动脉、颈内动脉C1段、大脑中动脉M1段及横窦处设置感兴趣点(POI),分别检测达峰时间(TTP)及相对达峰时间(rTTP)。同时收集CAS前后颈动脉狭窄段及颈内动脉C1段远端(管腔正常处)收缩期峰值流速(PSV)及舒张末期流速(EDV)。结果 CAS治疗后颈内动脉C1段及大脑中动脉M1段TTP及rTTP均较术前降低(P均<0.05),CAS治疗前后颈总动脉、横窦TTP及横窦rTTP差异均无统计学意义(P均>0.05)。CAS治疗后颈动脉狭窄段PSV及EDV均较术前降低,颈内动脉C1段远端PSV较术前升高(P均<0.05)。CAS治疗前后颈内动脉C1段TTP变化值与其远端(管腔正常处)超声参数PSV、EDV变化值均呈正相关(rs=0.500、0.522,P=0.049、0.038)。结论 CC-DSA可量化评估颈内动脉狭窄患者CAS治疗后血流动力学变化。
英文摘要:
      Objective To evaluate the feasibility of color coding of DSA (CC-DSA) in assessment of hemodynamic changes before and after carotid artery stenting (CAS). Methods Data of 16 patients with severe stenosis at the beginning of internal carotid artery who underwent CAS were analyzed retrospectively. DSA images before and after CAS were processed with CC-DSA software to get the corresponding color coded images. The points of interest (POI) were set up in common carotid artery, C1 segment of internal carotid artery, M1 segment of middle cerebral artery and transverse sinus, respectively, and the time to peak (TTP) as well as the relative time to peak (rTTP) of each POI were collected. Meanwhile, the peak systolic velocity (PSV) and end-diastolic velocity (EDV) of the anterior and posterior carotid artery stenosis segments and the distal end of the internal carotid artery C1 segment (normal lumen) were collected. Results TTP and rTTP of C1 segment of internal carotid artery and M1 segment of middle cerebral artery after CAS were lower than those before CAS (all P<0.05). No difference of TTP in common carotid artery, transverse sinus nor rTTP of common carotid artery was found before and after CAS (all P>0.05). Compared with those before CAS, PSV and EDV in carotid artery stenosis segment decreased, and PSV in the distal segment C1 of internal carotid artery increased after CAS (all P<0.05). The change value of TTP in C1 segment of internal carotid artery before and after CAS was positively correlated with the change values of PSV (rs=0.500, P=0.049) and EDV (rs=0.522, P=0.038) at the distal end. Conclusion CC-DSA can quantitatively evaluate the hemodynamic changes before and after CAS in patients with internal carotid artery stenosis.
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