沈倩,兰永树.静息心率对CTA评价冠状动脉弹性及病变的影响[J].中国介入影像与治疗学,2020,17(5):294-298
静息心率对CTA评价冠状动脉弹性及病变的影响
Impact of resting heart rate on evaluation of coronary artery elasticity and lesions during coronary CTA
投稿时间:2019-11-11  修订日期:2020-03-30
DOI:10.13929/j.issn.1672-8475.2020.05.009
中文关键词:  冠状动脉  心率  心血管造影术  弹性  斑块
英文关键词:coronary artery  heart rate  angiocardiography  elasticity  plaque
基金项目:
作者单位E-mail
沈倩 西南医科大学附属医院放射科, 四川 泸州 646000  
兰永树 西南医科大学附属医院放射科, 四川 泸州 646000 yblue2008@aliyun.com 
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中文摘要:
      目的 观察静息心率(RHR)对冠状动脉CTA(coronary CTA,CCTA)评价冠状动脉弹性及病变的影响。方法 回顾性分析180例接受CCTA检查患者,按RHR分组,A组RHR ≤ 60次/分,B组60次/分结果 A组RCA、LAD、LCX最佳重建时相均为40% R-R间期、70%或75% R-R间期,B组RCA、LAD、LCX最佳重建时相均为45%、75% R-R间期,C组RCA、LAD、LCX均为45%或50%、75%或80% R-R间期。3组正常亚组RCA、LAD、LCX血管弹性DC值差异均有统计学意义(P均<0.05),其中C组RCA、LAD、LCX的DC值均低于A组,LAD、LCX均低于B组(P均<0.05),A、B组间差异均无统计学意义(P均>0.05)。3组病变亚组RCA、LAD、LCX斑块数差异均有统计学意义(P均<0.05),其中C组RCA、LAD、LCX斑块数均多于A组,LAD斑块数多于B组(P均<0.05),A、B组间差异均无统计学意义(P均>0.05)。结论 CCTA检查中,患者RHR过高可致血管弹性降低及血管斑块数增加。
英文摘要:
      Objective To explore the impact of resting heart rate (RHR) on evaluation of coronary artery elasticity and lesions by coronary CTA (CCTA). Methods Data of 180 patients who underwent CCTA were retrospectively analyzed. The patients were divided into 3 groups according to RHR, i.e. group A, RHR ≤ 60 bpm, group B, RHR 60-80 bpm and group C, RHR ≥ 80 bpm (each n=60), and then were further divided into normal subgroup (no obvious lesion was found in CCTA) and diseased subgroup (CCTA found soft/hard plaques in coronary arteries) in each group. Data were reconstructed in 5% steps from 10% to 90% of the R-R interval, image quality was evaluated, and the best contraction and diastole reconstruction phases of right coronary artery (RCA), left anterior descending (LAD) and left circumflex branch (LCX) were obtained. Then distensibility coefficient (DC) of RCA, LAD and LCX in normal subgroups were measured at the best phase of 3 groups, and the number of plaques in the diseased subgroups were counted. Results The best reconstruction phases of RCA, LAD and LCX in group A were 40%, 70% or 75% R-R interval, in group B were 45% and 75%, while in group C were 45% or 50%, 75% or 80% R-R interval, respectively. Differences of DC values for RCA, LAD and LCX were statistically significant among 3 normal subgroups (all P<0.05). DC values of RCA, LAD and LCX in group C were lower than that in group A, of LAD and LCX were lower than those in group B (both P<0.05), whereas there was no significant difference between group A and B (both P>0.05). The differences of the number of plaques in RCA, LAD and LCX were statistically significant among 3 groups (all P<0.05). Plaques of RCA, LAD and LCX in group C were more than in group A, and of LAD was more than that in group B (all P<0.05), while no difference was found between group A and B (all P>0.05). Conclusion During CCTA examination, patients with too high RHR may present reduced vascular elasticity and increased number of vascular plaques.
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