韩祥,孙文阁.冠状动脉周围脂肪CT衰减与斑块类型的关系[J].中国介入影像与治疗学,2020,17(9):556-560
冠状动脉周围脂肪CT衰减与斑块类型的关系
Relationship of CT attenuation of pericoronary adipose tissue and plaque type
投稿时间:2020-02-12  修订日期:2020-07-16
DOI:10.13929/j.issn.1672-8475.2020.09.010
中文关键词:  冠状动脉  脂肪组织  动脉硬化  冠状动脉造影
英文关键词:coronary artery  adipose tissue  arteriosclerosis  coronary angiography
基金项目:
作者单位E-mail
韩祥 中国医科大学附属第一医院放射科, 辽宁 沈阳 110001  
孙文阁 中国医科大学附属第一医院放射科, 辽宁 沈阳 110001 wengesun@sina.com 
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中文摘要:
      目的 观察冠状动脉周围脂肪组织(PCAT)CT衰减与斑块类型之间的关系。方法 选取101例冠心病患者共196个斑块,包括非钙化斑块55个(A组)、混合斑块70个(B组)、钙化斑块71个(C组),比较3组斑块解剖特性指标及PCAT CT值,分析斑块周围PCAT CT值的影响因素,观察其与斑块中高衰减成分百分比之间的相关性。结果 3组间斑块最大横截面积、斑块体积、重构指数、病变狭窄程度、斑块中高衰减成分百分比、斑块平均CT值差异均有统计学意义(P均<0.05);A、B、C组斑块中高衰减成分百分比、平均CT值及PCAT CT值均依序增加,两两比较差异均有统计学意义(P均<0.05)。PCAT CT值与斑块中高衰减成分百分比呈正相关(r=0.677,P<0.05)。斑块中高衰减成分百分比是PCAT CT值升高的独立影响因素(OR=1.041,P<0.001)。结论 伴随冠状动脉粥样硬化进展,病变周围PCAT发生细胞组成成分及间质纤维化等组织重塑,影像学表现为CT值逐渐增加。
英文摘要:
      Objective To explore the relationship of CT attenuation of pericoronary adipose tissue (PCAT) and the underlying plaque types. Methods Totally 101 patients with coronary heart disease were enrolled. A total of 196 coronary artery plaques were detected, including 55 non-calcified plaques (group A), 70 mixed plaques (group B) and 71 calcified plaques (group C). The anatomical characteristic indices of plaques and the surrounding PCAT CT attenuation were measured and compared among 3 groups. The impact factors of PCAT attenuation and the correlation with the high-attenuation percentage in plaques were analyzed. Results Significant differences of the maximum plaque cross-sectional area, plaque volume, reconstruction index, degree of lesion stenosis, percentage of high-attenuation percentage in plaques and average CT value of plaques were found among 3 groups (all P<0.05). In group A, B and C, the high-attenuation percentage in plaques, the average CT values of plaques and PCAT gradually increased in turn, and differences between every 2 groups were all statistically significant (all P<0.05). CT value of PCAT was positively correlated with the high-attenuation percentage in plaques (r=0.677, P<0.05). The high-attenuation percentage in plaques was an independent factor affecting the increase of CT value of PCAT (OR=1.041, P<0.001). Conclusion With the increase of the percentage of high-attenuation percentage in coronary artery plaques, the progression of coronary atherosclerosis, cellular components and interstitial fibrosis and other tissue remodeling occur around the lesion in PCAT, presenting as gradually increasing CT values on CT images.
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