张肖,张晶,李竞,张啸波,孟亮亮,肖越勇.明胶海绵-血凝酶封堵剂用于肺穿刺活检的临床效果[J].中国介入影像与治疗学,2021,18(1):4-7
明胶海绵-血凝酶封堵剂用于肺穿刺活检的临床效果
Clinical effects of gelatin sponge-snake venom hemagglutinin blocking agent applicated in lung puncture biopsy
投稿时间:2020-11-07  修订日期:2020-12-08
DOI:10.13929/j.issn.1672-8475.2021.01.002
中文关键词:  肺肿瘤  明胶海绵,吸收性  活组织检查  并发症  蛇毒血凝酶
英文关键词:lung neoplasms  gelatin sponge, absorbable  biopsy  complications  snake venom hemagglutinin
基金项目:北京市科技新星计划(Z181100006218026)。
作者单位E-mail
张肖 中国人民解放军总医院第一医学中心放射诊断科, 北京 100853  
张晶 中国人民解放军总医院第一医学中心放射诊断科, 北京 100853  
李竞 中国人民解放军总医院第一医学中心放射诊断科, 北京 100853
中国人民武装警察部队特色医学中心医学影像科, 天津 300162 
 
张啸波 中国人民解放军总医院第一医学中心放射诊断科, 北京 100853  
孟亮亮 中国人民解放军总医院第一医学中心放射诊断科, 北京 100853  
肖越勇 中国人民解放军总医院第一医学中心放射诊断科, 北京 100853 xiaoyueyong@vip.sina.com 
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中文摘要:
      目的 观察明胶海绵-血凝酶封堵剂在肺穿刺活检中的临床应用价值。方法 回顾性分析586例接受CT引导下肺部病变穿刺活检患者,均于穿刺取材后以明胶海绵-血凝酶混合物作为封堵剂进行封堵,观察活检效果及术后并发症。结果 对所有患者均成功实施穿刺活检手术。术后出血89例(89/586,15.19%),包括邻近肺小叶出血(23/89,25.84%)、针道出血(60/89,67.42%)和胸腔内出血(6/89,6.74%);气胸45例(45/586,7.68%),其中8例(8/45,17.78%)为中量至大量气胸;经对症处理后患者均恢复良好,无严重并发症发生。结论 注射明胶海绵-血凝酶混合物行封堵可显著降低肺穿刺机械性损伤造成的肺出血、气胸等并发症,操作方便且安全性好。
英文摘要:
      Objective To investigate the clinical application value of injecting gelatin sponge-snake venom hemagglutinin mixed sealant in lung puncture biopsy. Methods Totally 586 patients with pulmonary lesions who underwent CT-guided needle biopsy were retrospectively analyzed. Gelatin sponge hemagglutinin mixed blocking agent were given after punctures, and the effect of biopsy and postoperative complications were observed. Results Puncture biopsy was performed successfully in all patients. There were 89 patients (89/586, 15.19%) with postoperative hemorrhage, including 23 cases of adjacent lobules hemorrhage (23/89, 25.84%), 60 cases of needle hemorrhage (60/89, 67.42%) and 6 cases of intrathoracic hemorrhage (6/89, 6.74%). Pneumothorax occurred in 45 cases (45/586, 7.68%), among them 8 were found with moderate to large pneumothorax (8/45, 17.78%). All patients recovered well after symptomatic treatment, and no serious complication occurred. Conclusion Injecting gelatin sponge-snake hemagglutinin mixed sealant could significantly reduce the incidence of pulmonary hemorrhage and pneumothorax caused by puncture mechanical injury during lung puncture biopsy, which was easy to operate and safe.
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