李炯,徐浩,许锦,尹瑞瑞,张欣贤.无水乙醇联合泡沫硬化治疗儿童体表静脉畸形[J].中国介入影像与治疗学,2021,18(2):83-86
无水乙醇联合泡沫硬化治疗儿童体表静脉畸形
Absolute ethanol combined with foam sclerotherapy for treatment of superficial venous malformations in children
投稿时间:2020-10-15  修订日期:2021-01-04
DOI:10.13929/j.issn.1672-8475.2021.02.005
中文关键词:  动静脉畸形  硬化疗法  儿童  介入放射学
英文关键词:arteriovenous malformations  sclerotherapy  child  interventional radiology
基金项目:江苏省青年医学人才项目(QNRC2016374)。
作者单位E-mail
李炯 徐州医科大学附属徐州儿童医院介入科, 江苏 徐州 221000  
徐浩 徐州医科大学附属医院介入科, 江苏 徐州 221000 xuhao585@126.com 
许锦 徐州医科大学附属徐州儿童医院药学部, 江苏 徐州 221000  
尹瑞瑞 徐州医科大学附属徐州儿童医院皮肤科, 江苏 徐州 221000  
张欣贤 徐州医科大学附属徐州儿童医院介入科, 江苏 徐州 221000  
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中文摘要:
      目的 观察无水乙醇联合泡沫硬化治疗体表静脉畸形(VM)患儿的有效性及安全性。方法 回顾性分析接受DSA引导下无水乙醇联合聚桂醇泡沫硬化治疗的42例体表VM患儿,术后随访观察治疗效果及不良反应。结果 共行79次硬化治疗,平均每例(1.1±0.2)次;总有效率97.62%(41/42)。79例次硬化治疗中,24例次术后疼痛明显,65例次术后病灶明显肿胀;12例次术后低热,对症治疗缓解或自行缓解;1例次术后局部坏死,经对症治疗3个月后瘢痕愈合;未发生过敏、异位栓塞及肺动脉高压等严重并发症。结论 无水乙醇联合泡沫硬化治疗儿童体表VM安全有效。
英文摘要:
      Objective To observe the efficacy and safety of absolute ethanol combined with foam sclerotherapy for superficial venous malformations (VM) in children. Methods Data of 42 children with superficial VM were retrospectively analyzed. All children underwent DSA-guided absolute ethanol combined with lauromacrogol foam sclerotherapy, and then follow-up was conducted to observe the therapeutic effect and adverse reactions. Results All 79 sclerotherapy sessions were performed in 42 children, with an average of (1.1±0.2)times, and the total effective rate was 97.62% (41/42). Obvious postoperative pain occurred in 24 cases, while obvious postoperative swelling was observed in 65 cases. Low postoperative fever happened in 12 cases, which relieved after symptomatic treatment or self remission. Local necrosis occurred in 1 case and healed 3 months after symptomatic treatment and left scars. No severe complication such as allergy, ectopic embolism nor pulmonary hypertension occurred. Conclusion Absolute ethanol combined with foam sclerotherapy was safe and effective for treating superficial VM in children.
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