| 薛亚娥,姚彦武,张雪婷,张明华,周祖邦.超声引导下微波消融治疗原发性甲状旁腺功能亢进症术后复发影响因素[J].中国介入影像与治疗学,2021,18(10):596-599 |
| 超声引导下微波消融治疗原发性甲状旁腺功能亢进症术后复发影响因素 |
| Impact factors of recurrence of hyperparathyroidism after ultrasound-guided microwave ablation |
| 投稿时间：2021-07-04 修订日期：2021-09-02 |
| DOI：10.13929/j.issn.1672-8475.2021.10.005 |
| 中文关键词: 甲状旁腺功能亢进症 超声检查 微波消融 复发 |
| 英文关键词:hyperparathyroidism ultrasonography microwave ablation recurrence |
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| 中文摘要: |
| 目的 分析超声引导下微波消融（MWA）治疗原发性甲状旁腺功能亢进症（PHPT）术后复发的影响因素。方法 回顾性分析经超声引导下MWA治疗的37例PHPT患者，术后随访12个月，观察是否复发，分析其影响因素。结果 37例PHPT患者共51枚甲状旁腺结节，均获一次性完全消融。随访期间9例（9/37，24.32%）于术后7个月内复发；复发与未复发患者之间，年龄、单枚结节体积、血钙及血清1，25-二羟维生素D3[1，25（OH）2D3]水平差异均有统计学意义（P均<0.05），其余参数差异均无统计学意义（P均>0.05）。多因素Logistic回归分析显示，1，25（OH）2D3是PHPT经MWA治疗后复发的独立影响因素[OR=3.154，95%CI（1.423，5.641），P<0.05]。结论 1，25（OH）2D3缺乏为超声引导下MWA治疗PHPT术后复发的独立危险因素。 |
| 英文摘要: |
| Objective To analyze the impact factors of recurrence of primary hyperparathyroidism (PHPT) after ultrasound-guided microwave ablation (MWA). Methods Data of 37 patients with PHPT who underwent ultrasound-guided MWA were retrospectively analyzed. A 12 months' follow-up was performed after ablation to observe recurrence or not and screen the impact factors of recurrence. Results Totally 51 parathyroid nodules in 37 PHPT patients were completely ablated in single procedures. During follow-up periods, recurrence of hyperparathyroidism was observed in 9 patients (9/37, 24.32%) within 7 months after ablation. Statistical significant differences of age, single nolular volume, serum calcium and 1,25-dihydroxyvitamin D3 (1,25[OH]2D3) level were found between recurrent and non-recurrent patients (all P<0.05), but not of other parameters (all P>0.05). Multivariate Logistic regression analysis showed that 1,25 (OH)2D3 was an independent predictor of recurrence of hyperparathyroidism after MWA (OR=3.154, 95%CI[1.423, 5.641], P<0.05). Conclusion 1,25(OH)2D3 deficiency was an independent risk factor for recurrence of hyperparathyroidism after ultrasound-guided MWA. |
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