李昀霖,谭水莲,于晓玲,梁萍,姚俊东,程志刚,韩治宇,刘方义,于杰.微波消融治疗胆肠吻合术后肝脏恶性肿瘤术前肠道准备及应用抗生素对降低术后并发症的效果[J].中国介入影像与治疗学,2022,19(6):329-332
微波消融治疗胆肠吻合术后肝脏恶性肿瘤术前肠道准备及应用抗生素对降低术后并发症的效果
Effects of bowel preparation combined with antibiotics before microwave ablation of liver malignancies after biliary-enteric anastomosis for reducing incidence and severity of complications
投稿时间:2021-11-30  修订日期:2022-01-19
DOI:10.13929/j.issn.1672-8475.2022.06.003
中文关键词:  肝肿瘤  胆管肠吻合术,肝  肠道准备  抗生素  肝脓肿  并发症  超声检查  微波消融
英文关键词:liver neoplasms  portoenterostomy, hepatic  bowel preparation  antibiotics  liver abscess  complications  ultrasonography  microwave ablation
基金项目:国家自然科学基金(82172027)。
作者单位E-mail
李昀霖 解放军医学院, 北京 100853
中国人民解放军总医院第五医学中心介入超声科, 北京 100853 
 
谭水莲 中国人民解放军总医院第五医学中心介入超声科, 北京 100853  
于晓玲 中国人民解放军总医院第五医学中心介入超声科, 北京 100853 dyuxl301@aliyun.com 
梁萍 中国人民解放军总医院第五医学中心介入超声科, 北京 100853  
姚俊东 中国人民解放军总医院第五医学中心介入超声科, 北京 100853  
程志刚 中国人民解放军总医院第五医学中心介入超声科, 北京 100853  
韩治宇 中国人民解放军总医院第五医学中心介入超声科, 北京 100853  
刘方义 中国人民解放军总医院第五医学中心介入超声科, 北京 100853  
于杰 中国人民解放军总医院第五医学中心介入超声科, 北京 100853  
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中文摘要:
      目的 观察超声引导下微波消融(MWA)治疗胆肠吻合术(BEA)后肝脏恶性肿瘤术前肠道准备及应用抗生素对降低术后并发症及其严重程度的价值。方法 回顾性分析31例接受超声引导下MWA的BEA后肝脏恶性肿瘤患者,其中17例MWA前接受(A组)、14例(B组)未接受肠道准备及应用抗生素,对比观察2组术后并发症发生率及严重程度。结果 2组患者基线特征及原发肿瘤类型差异均无统计学意义(P均>0.05)。31例均顺利完成MWA。MWA后A组住院时间、发热率、发热持续时间、菌血症发生率及肝脓肿发生率均低于B组(P均<0.05)。结论 MWA治疗BEA后肝脏恶性肿瘤患者术前肠道准备及合理应用抗生素可明显降低术后并发症发生率及严重程度。
英文摘要:
      Objective To observe the value of bowel preparation combined with application antibiotics before ultrasound-guided microwave ablation (MWA) of liver malignancies for reducing the incidence and severity of complications after biliary-enteric anastomosis(BEA). Methods Data of 31 patients with liver malignancies after BEA biliary-enteric anastomosis and underwent ultrasound-guided MWA were retrospectively analyzed. The patients were divided into group A (with bowel preparation combined with antibiotics before MWA, n=17) and group B (no bowel preparation nor antibiotics before MWA, n=14). The incidence and severity of complications were observed and compared between groups. Results MWA of liver malignancy was successfully completed in all 31 patients. There was no significant difference of baseline characteristics nor primary tumor types between groups (all P>0.05). The hospitalization time, fever rate, fever duration, the incidence of bacteremia and liver abscess after MWA in group A were lower than those in group B (all P<0.05). Conclusion Bowel preparation combined with reasonable antibiotics could obviously reduce the incidence and severity of complications of MWA for treating liver malignancies in patients after BEA.
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