顾怡栋,汪璐赟,邓学东,杨慎敏,姜纬.声触诊组织成像定量技术用于非梗阻性无精子症睾丸精子抽吸术[J].中国介入影像与治疗学,2022,19(11):697-700
声触诊组织成像定量技术用于非梗阻性无精子症睾丸精子抽吸术
Virtual touch tissue imaging quantification applicated in testicular sperm aspiration of non-obstructive azoospermia
投稿时间:2022-06-22  修订日期:2022-08-08
DOI:10.13929/j.issn.1672-8475.2022.11.006
中文关键词:  无精子症  不育,男性  睾丸  超声检查  弹性成像技术
英文关键词:azoospermia  infertility,male  testis  ultrasonography  elasticity imaging techniques
基金项目:南京医科大学科技发展基金(NMUB20210279)。
作者单位E-mail
顾怡栋 南京医科大学附属苏州医院 苏州市立医院超声中心, 江苏 苏州 215002  
汪璐赟 南京医科大学附属苏州医院 生殖与遗传中心, 江苏 苏州 215002 luyunwang123@163.com 
邓学东 南京医科大学附属苏州医院 苏州市立医院超声中心, 江苏 苏州 215002  
杨慎敏 南京医科大学附属苏州医院 生殖与遗传中心, 江苏 苏州 215002  
姜纬 南京医科大学附属苏州医院 苏州市立医院超声中心, 江苏 苏州 215002  
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中文摘要:
      目的 观察声触诊组织成像定量(VTIQ)技术用于非梗阻性无精子症(NOA)睾丸精子抽吸术(TESA)的价值。 方法 前瞻性纳入60例NOA患者,随机分为VTIQ组和常规组,每组30例;选择于VTIQ组VTIQ示睾丸剪切波速度(SWV)最小处和常规组睾丸中部最厚处行TESA,观察组间获精率差异,分析VTIQ用于TESA的价值。结果 组间患者年龄、不育年限、睾丸体积、促卵泡激素(FSH)、促黄体生成激素(LH)、睾酮(T)、雌二醇(E2)及抗米勒管激素(AMH)差异均无统计学意义(P均>0.05);VTIQ组总获精率显著高于常规组(χ2=6.79,P<0.05)。VTIQ组获精处睾丸穿刺点的SWV为(1.44±0.31)m/s;以SWV=1.63 m/s为截断值,选择睾丸最优穿刺点行TESA的约登指数为0.75,敏感度和特异度分别为91.70%和83.30%。结论 VTIQ有助于TESA前评估NOA患者睾丸组织弹性及选择最优穿刺点。
英文摘要:
      Objective To observe the value of virtual touch tissue imaging quantification (VTIQ) applicated in testicular sperm aspiration (TESA) of non-obstructive azoospermia (NOS). Methods A total of 60 NOA patients were prospectively enrolled and randomly divided into VTIQ group and routine group (each n=30). TESA was performed on the area with the minimum shear wave velocity (SWV) shown with VTIQ of VTIQ group and the thickest part of middle testis of routine group. The obtaining rates of sperm were compared between 2 groups, and the value of VTIQ for TESA was analyzed. Results There was no significant difference of patients' age, the years of infertility, testicular volume, follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T), estradiol (E2) nor anti-Müllerian hormone (AMH) between groups (all P>0.05), while the total obtaining rate of sperm of VTIQ group was significant higher than that of routine group (χ2=6.79, P<0.05). SWV at the testicular puncture point of successful TESA for obtaining sperm was (1.44±0.31)m/s. Taken SWV=1.63 m/s as the cut-off value, the Youden index of selecting the optimal puncture point of TESA for testis was 0.75, the sensitivity and specificity was 91.70% and 83.30%, respectively. Conclusion VTIQ was helpful for evaluating the elasticity of testicular tissue of NOA patients and selecting the optimal puncture point of testis before TESA.
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