王睿婕,董秀娟,解艳华,黄辉,李坤,许瑶璇,左云鹏.中晚期胎儿肝区脐血流分布状态与胎龄及生长指标的相关性[J].中国介入影像与治疗学,2022,19(11):705-709
中晚期胎儿肝区脐血流分布状态与胎龄及生长指标的相关性
Correlations of liver region distribution of umbilical blood flow at the middle and third trimester with gestational age and growth indicators
投稿时间:2022-07-12  修订日期:2022-08-13
DOI:10.13929/j.issn.1672-8475.2022.11.008
中文关键词:  胎儿  脐静脉  门静脉  血流动力学  超声检查,产前
英文关键词:fetus  umbilical vein  portal vein  hemodynamics  ultrasonography,prenatal
基金项目:徐州市卫生健康委科技计划项目(XWKYHT20200032)。
作者单位E-mail
王睿婕 徐州医科大学附属徐州妇幼保健院 超声科, 江苏 徐州 221009  
董秀娟 徐州医科大学附属徐州妇幼保健院 超声科, 江苏 徐州 221009 64922607@qq.com 
解艳华 徐州医科大学附属徐州妇幼保健院 超声科, 江苏 徐州 221009  
黄辉 徐州医科大学附属徐州妇幼保健院 统计室, 江苏 徐州 221009  
李坤 徐州医科大学附属徐州妇幼保健院 超声科, 江苏 徐州 221009  
许瑶璇 徐州医科大学附属徐州妇幼保健院 超声科, 江苏 徐州 221009  
左云鹏 徐州医科大学附属徐州妇幼保健院 超声科, 江苏 徐州 221009  
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中文摘要:
      目的 分析妊娠中晚期胎儿肝区脐血流分布状态与胎龄及生长指标的相关性。方法 对714胎胎龄17~40+6周发育正常胎儿行超声检查,记录胎儿生长指标,包括双顶径、头围、腹围、股骨长及体质量;测量胎儿脐静脉(UV)腹内段(DUV)、门静脉窦(PS)起始段(DPS)、静脉导管(DV)起始段(DDV)内径及其相应最大血流速度VUV、VPS和VDV,计算UV、DV、左门静脉(LPV)及右门静脉(RPV)血流量,即QUV、QDV、QLPV、QRPV;分析脐血流相关参数与胎龄及生长指标的相关性。结果 胎儿DUV、DPS、DDV及VUV、VPS均与胎龄呈正相关(r=0.907、0.901、0.874、0.393、0.301,P均<0.001),VDV与胎龄无明显相关性 (P=0.817);胎儿QUV、QDV、QLPV及QRPV与胎龄呈正相关(rs=0.904、0.895、0.797、0.761,P均<0.05)。 DV分流率与胎龄及双顶径、头围、腹围、股骨长及体质量均呈负相关(rs=-0.302、-0.306、-0.311、-0.332、-0.304、-0.321,P均<0.001),LPV分流率与上述参数均呈正相关(rs=0.245、0.221、0.228、0.236、0.230、0.230,P均<0.001),RPV分流率与上述参数均无明显相关性(P均>0.05)。结论 妊娠中晚期胎儿肝区脐血流分布状态与胎龄及生长指标具有一定相关性。
英文摘要:
      Objective To explore the correlations of distribution status of umbilical blood flow in liver region at the middle and third trimester with gestational age (GA) and growth indicators. Methods Ultrasonography was performed on 714 fetuses with GA with GA of 17—40+6 weeks. Fetal growth indicators, including biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC), femur length (FL) and body weight were recorded. Internal diameter (DUV, DPS, DDV) of abdominal segment of umbilical vein (UV), portal sinus (PS) and the beginning segment of ductus venosus (DV), also the corresponding maximum blood flow velocity (VUV, VPS, VDV) were measured, and the volume of blood flow within UV, DV, left portal vein (LPV) and right portal vein (RPV), i.e. QUV, QDV, QLPV and QRPV were calculated. The correlations of fetal umbilical blood flow related parameters with GA and growth indicators were analyzed. Results Fetal DUV, DPS, DDV, VUV and VPS were positively correlated with GA (r=0.907, 0.901, 0.874, 0.393 and 0.301, all P<0.001), while no significant correlation of VDV with GA was found (P=0.817). Fetal QUV, QDV, QLPV and QRPV were positively correlated with GA (rs=0.904, 0.895, 0.797 and 0.761, all P<0.05). DV shunt rate were negatively correlated with GA and growth indicators BPD, HC, AC, FL and body weight (rs=-0.302, -0.306, -0.311, -0.332, -0.304, -0.321, all P<0.001), while LPV shunt rate was positively correlated with the above parameters (rs=0.245, 0.221, 0.228, 0.236, 0.230, 0.230, all P<0.001), but RPV shunt rate was not correlated with the above parameters (all P>0.05). Conclusion Fetal umbilical blood flow distribution in the liver region at the middle and third trimester had certain correlations with GA and growth indicators.
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