冯庆,李涛,李筱漾,梁洪峰,陈赛琼,彭鹏.CT鉴别诊断造血干细胞移植后胃肠道移植物抗宿主病与机会性感染性肠炎[J].中国介入影像与治疗学,2022,19(11):710-714
CT鉴别诊断造血干细胞移植后胃肠道移植物抗宿主病与机会性感染性肠炎
CT for differential diagnosis of gastrointestinal graft versus host disease and opportunistic infectious enteritis after hematopoietic stem cell transplantation
投稿时间:2022-04-30  修订日期:2022-05-23
DOI:10.13929/j.issn.1672-8475.2022.11.009
中文关键词:  造血干细胞移植  胃肠道  移植物抗宿主病  体层摄影术,X线计算机
英文关键词:hematopoietic stem cell transplantation  gastrointestinal tract  graft versus host disease  tomography,X-ray computed
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作者单位E-mail
冯庆 广西医科大学第一附属医院放射科, 广西 南宁 530021
柳州市工人医院放射科, 广西 柳州 545000 
 
李涛 柳州市工人医院放射科, 广西 柳州 545000  
李筱漾 柳州市工人医院放射科, 广西 柳州 545000  
梁洪峰 柳州市工人医院放射科, 广西 柳州 545000  
陈赛琼 柳州市工人医院放射科, 广西 柳州 545000  
彭鹏 广西医科大学第一附属医院放射科, 广西 南宁 530021 doublep@126.com 
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中文摘要:
      目的 观察CT鉴别诊断造血干细胞移植(HSCT)后胃肠道移植物抗宿主病(GI-GVHD)与机会性感染性肠炎的价值。方法 回顾性分析59例HSCT后出现胃肠道症状且经内窥镜下组织活检病理确诊GI-GVHD(GI-GVHD组,n=31)或机会性感染性肠炎(机会性感染性肠炎组,n=28)患者,观察其CT表现差异。结果 GI-GVHD组CT显示肠壁增厚、肠壁强化、肠管积气及肠外CT表现肠周淋巴结增生、胆囊炎、膀胱炎或膀胱出血率均高于机会性感染性肠炎组(P均<0.05),而CT显示多灶性肠壁炎症及肠系膜水肿率组间差异均无统计学意义(P均>0.05)。结论 CT有助于鉴别诊断HSCT后GI-GVHD与机会性感染性肠炎。
英文摘要:
      Objective To explore the value of CT for differential diagnosis of gastrointestinal graft versus host disease (GI-GVHD) and opportunistic infectious enteritis after hematopoietic stem cell transplantation (HSCT). Methods Fifty-nine patients with gastrointestinal symptoms after HSCT and pathologically confirmed GI-GVHD (GI-GVHD group, n=31) or opportunistic infectious enteritis (opportunistic infectious enteritis group, n=28) through endoscopic tissue biopsy were retrospectively observed, and the CT manifestations were comparatively analyzed. Results The incidence of intestinal wall thickening, intestinal wall enhancement, intestinal pneumatosis of intestinal CT manifestations and periintestinal lymph node hyperplasia, cholecystitis, cystitis or bladder hemorrhage in GI-GVHD group were all higher than those in opportunistic infectious enteritis group (all P<0.05), while there was no significant difference of the incidence of multifocal intestinal wall inflammation nor mesenteric edema between groups (both P>0.05). Conclusion CT was helpful for differential diagnosis of GI-GVHD and opportunistic infective enteritis after HSCT.
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