| 罗霞,何萍,杨鑫,张菊英,蒋琼,冯琳莉,李韩梅,唐小清,杨友,余进洪.冷循环液温度对微波消融离体猪肝消融灶形态的影响[J].中国介入影像与治疗学,2024,21(5):294-297 |
| 冷循环液温度对微波消融离体猪肝消融灶形态的影响 |
| Impact of cold circulation liquid temperature on ablation focus morphology of microwave ablation for porcine liver in vitro |
| 投稿时间：2024-03-17 修订日期：2024-04-23 |
| DOI：10.13929/j.issn.1672-8475.2024.05.009 |
| 中文关键词: 消融技术 动物实验 猪肝 |
| 英文关键词:ablation techniques animal experimentation porcine liver |
| 基金项目: |
| 作者 | 单位 | E-mail | | 罗霞 | 川北医学院附属医院超声科, 四川 南充 637000 | | | 何萍 | 川北医学院附属医院超声科, 四川 南充 637000 | | | 杨鑫 | 川北医学院附属医院超声科, 四川 南充 637000 | | | 张菊英 | 川北医学院附属医院超声科, 四川 南充 637000 | | | 蒋琼 | 川北医学院附属医院超声科, 四川 南充 637000 | | | 冯琳莉 | 川北医学院附属医院超声科, 四川 南充 637000 | | | 李韩梅 | 川北医学院附属医院超声科, 四川 南充 637000 | | | 唐小清 | 川北医学院附属医院超声科, 四川 南充 637000 | | | 杨友 | 川北医学院附属医院超声科, 四川 南充 637000 | | | 余进洪 | 川北医学院附属医院超声科, 四川 南充 637000 | yujinhong@nsmc.edu.cn |
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| 中文摘要: |
| 目的 观察冷循环液温度对微波消融（MWA）离体猪肝消融灶形态的影响。方法 将20块新鲜离体猪肝组织随机分为冰水冷循环组（A组）及常温冷循环组（B组），分别以不同消融功率（50、60、70 W）及消融时间（1、5 min）于各亚组，即A1与B1（50 W，1 min）、A2与B2（50 W，5 min）、A3与B3（60 W，1 min）、A4与B4（60 W，5 min）、A5与B5（70 W，1 min）及A6与B6（70 W，5 min）亚组内各消融10个靶区。对比A、B组相同条件亚组间及组内消融灶形态，包括消融灶纵向直径（LD）、横向直径（TD）、球形指数（RI）及体积（V）。结果 相同消融功率及时间下，A组各亚组消融灶LD均小于B组（P均＜0.05）；A1 与B1、A2与B2、A4与B4、A5与B5、A6与B6亚组之间，前者消融灶RI均大于后者（P均＜0.05），而A3与B3亚组间消融灶RI差异无统计学意义（P＞0.05）。冷循环液温度对2组消融灶TD（F=1.125）和V（F=3.332）的主效应均不显著（P均≥0.05）。相同冷循环液温度条件下，A1与A2、A3与A4、A5与A6各亚组间消融灶形态各参数差异均有统计学意义（P均＜0.05），B组各亚组间亦然。结论 以恒定消融功率及时间行MWA消融离体猪肝时，采用冰水冷循环可使消融灶形态更接近于球形；且随消融时间延长，消融灶范围越大，则RI越高。 |
| 英文摘要: |
| Objective To observe the impact of cold circulation liquid temperature on ablation focus morphology of microwave ablation (MWA) for in vitro porcine liver tissue. Methods Twenty in vitro fresh porcine liver blocks were randomly divided into ice water circulation group (group A) and normal temperature circulation group (group B), respectively. Ten target ablations in each subgroups in group A and group B, i.e. A1 and B1 (50 W, 1 min), A2 and B2 (50 W, 5 min), A3 and B3 (60 W, 1 min), A4 and B4 (60 W, 5 min), A5 and B5 (70 W, 1 min) as well as A6 and B6 (70 W, 5 min) subgroups were performed using different ablation power (50, 60, 70 W) and ablation time (1, 5 min), respectively. Then the morphology indexes of ablation foci, including longitudinal diameter (LD), transverse diameter (TD), roundness index (RI) and volume (V) were compared between subgroups in group A and B, also among subgroups within group A and B. Results Under the same ablation power and time, LD of ablation foci in subgroups of group A were all smaller than those of group B (all P<0.05). Significant differences of RI of ablation foci were found between A1 and B1, A2 and B2, A4 and B4, A5 and B5 as well as A6 and B6 subgroups (all P<0.05), but not between A3 and B3 subgroups (P>0.05). However, the main effect of cold circulation liquid temperature on ablation focus TD (F=1.125) nor V (F=3.332) was not significant (both P ≥ 0.05). Under the same cold circulation liquid temperature, significant differences of the morphology indexes of ablation foci were detected between A1 and A2, A3 and A4 as well as A5 and A6 subgroups, also between corresponding subgroups in group B (all P<0.05). Conclusion During MWA for in vitro porcine liver tissue under constant ablation power and time, taken ice water as the cold circulation liquid was benefit to ablation focus shaped spherically. With the extension of ablation time, the larger the ablation focus, the higher the RI. |
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