| 汪朝霞 综述,王志刚 审校.超声微泡造影剂携基因或药物治疗研究[J].中国介入影像与治疗学,2006,3(4):306-308 |
| 超声微泡造影剂携基因或药物治疗研究 |
| Treatment of ultrasound contrast agents for gene or drug delivery |
| 投稿时间：2005-10-11 修订日期：2006-04-12 |
| DOI： |
| 中文关键词: 超声检查 微泡 携基因和药物
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| 英文关键词:Ultrasonography Microbubble Gene or drug delivery |
| 基金项目: |
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| 摘要点击次数: 17312 |
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| 中文摘要: |
| 超声微泡造影剂经静脉注射到靶组织后,在超声能量作用下,因"空化效应",能有效穿透血管内皮屏障,定向释放内部包裹的基因或药物,使局部浓度大大增高,达到靶向治疗目的。微泡可能成为靶向治疗的载体,超声造影剂作为一种新型、无创的运载系统具有广阔的应用前景。
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| 英文摘要: |
| The ultrasound microbubble agents cavitate after intravenous injection by ultrasound energy. The genes or drugs incorporated in the microbubbles can pass across the endothelial cell barrier effectively, which reach the sufficient local concentrations at the specific tissue area and achieve target treatment effect.Microbubble may be a vector for target treatment. Therefore, ultrasound contrast agent as an new and non-invasive vector for treatment holds considerable promises. |
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