| 谭丽丽,田晞,张骞,冯莉莉,张旭,刘钢,王曼.高b值DWI诊断乳腺良恶性病变:Meta分析[J].中国医学影像技术,2020,36(9):1324~1329 |
| 高b值DWI诊断乳腺良恶性病变:Meta分析 |
| Diagnostic value of DWI with high b value in diagnosis of benign and malignant breast lesions: Meta-analysis |
| 投稿时间：2019-11-22 修订日期：2020-08-08 |
| DOI：10.13929/j.issn.1003-3289.2020.09.012 |
| 中文关键词: 乳腺肿瘤 弥散磁共振成像 Meta分析 |
| 英文关键词:breast neoplasms diffusion magnetic resonance imaging meta-analysis |
| 基金项目: |
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| 摘要点击次数: 2012 |
| 全文下载次数: 696 |
| 中文摘要: |
| 目的 采用Meta分析评价高b值DWI诊断乳腺良恶性病变的价值。方法 检索PubMed、Embase、Cochrane Library、万方医学网、中国知网及维普数据库自建库至2019年10月发表的关于高b值DWI评估乳腺良恶性病变的中英文文献，对最终纳入文献进行质量评估及数据提取。采用Meta-Disc 1.4软件进行统计分析，检验各研究间异质性，绘制森林图及综合受试者工作特征（SROC）曲线，计算曲线下面积（AUC）。采用Stata 15.0软件进行发表偏倚检验。结果 最终纳入18篇文献。高b值DWI评估乳腺良恶性病变的合并敏感度为0.88，合并特异度为0.84，合并诊断比值比为51.97；SROC的AUC为0.94，Q指数为0.88。结论 高b值DWI诊断乳腺良恶性病变的敏感度和特异度均较高，可用于鉴别诊断乳腺良恶性病变。 |
| 英文摘要: |
| Objective To explore the diagnostic value of DWI with high b value for benign and malignant breast lesions. Methods PubMed, Embase, Cochrane Library, Wanfang Med Online, CNKI and VIP databases were searched from the establishment of database to October 2019. Chinese and English literature about the observation of benign and malignant breast lesions with high b value DWI were included, and the quality evaluation and data extraction of the final included articles were carried out. Meta-Disc 1.4 software was used for statistical analysis to test the heterogeneity of the studies, the forest map and the summary receiver operating characteristic (SROC) curve were drawn, and area under the curve (AUC) was calculated. Stata 15.0 software was used to test publication bias. Results Totally 18 eligible articles were included for meta-analysis, the pooled sensitivity of high b value DWI in evaluating benign and malignant breast lesions was 0.88, the pooled specificity was 0.84, the ratio of the pooled diagnostic ratio was 51.97, and the AUC of SROC was 0.94, Q index was 0.88. Conclusion The sensitivity and specificity of DWI with high b value in diagnosis of benign and malignant breast lesions were both high, which could be used in differential diagnosis of benign and malignant breast lesions. |
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