| 王璐,辛军.分子影像探针早期诊断肝纤维化研究进展[J].中国医学影像技术,2020,36(9):1400~1404 |
| 分子影像探针早期诊断肝纤维化研究进展 |
| Research advances of molecular probes for early diagnosis of liver fibrosis |
| 投稿时间：2019-06-18 修订日期：2020-03-03 |
| DOI：10.13929/j.issn.1003-3289.2020.09.030 |
| 中文关键词: 肝硬化 诊断显像 分子成像 分子探针技术 |
| 英文关键词:liver cirrhosis diagnostic imaging molecular imaging molecular probe techniques |
| 基金项目:辽宁省重点研发计划攻关项目（2017225030）、沈阳市科学技术计划项目（18014423）。 |
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| 中文摘要: |
| 肝纤维化早期具有可逆性及可治愈性，早期诊断肝纤维化及判断其程度具有重要意义。针对肝纤维化发生发展中异常表达分子构建的靶向探针能精准、无创地整合人体生理、病理代谢分子信息，有利于早期及特异性诊断纤维化。本文针对分子探针早期诊断肝纤维化研究进展进行综述。 |
| 英文摘要: |
| Early liver fibrosis is reversible and curable. Therefore, early diagnosis and staging of liver fibrosis are of great clinical significance. Targeting at the abnormal expression molecules in development of liver fibrosis, molecular probes are constructed as precise and non-invasive methods to integrate the information of human physiological and pathological metabolism, which is beneficial to early and specific diagnosis of fibrosis. The advances in molecular probes for early diagnosis and staging of liver fibrosis were reviewed in this article. |
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