黄文静,李鑫,王俊,樊凤仙,张鹏飞,张静.成人型神经元核内包涵体病MRI表现[J].中国医学影像技术,2021,37(9):1281~1285
成人型神经元核内包涵体病MRI表现
MRI manifestations of adult-onset neuronal intranuclear inclusion disease
投稿时间:2020-07-17  修订日期:2021-06-21
DOI:10.13929/j.issn.1003-3289.2021.09.001
中文关键词:  神经元核内包涵体病  磁共振成像
英文关键词:neuronal intranuclear inclusion disease  magnetic resonance imaging
基金项目:国家自然科学基金(81960309)、兰州大学第二医院"萃英科技创新"计划(CY2018-MS02)。
作者单位E-mail
黄文静 兰州大学第二医院核磁科, 甘肃 兰州 730000  
李鑫 兰州大学第二医院神经内科, 甘肃 兰州 730000  
王俊 兰州大学第二医院核磁科, 甘肃 兰州 730000  
樊凤仙 兰州大学第二医院核磁科, 甘肃 兰州 730000  
张鹏飞 兰州大学第二医院核磁科, 甘肃 兰州 730000  
张静 兰州大学第二医院核磁科, 甘肃 兰州 730000 lztong2001@163.com 
摘要点击次数: 1166
全文下载次数: 422
中文摘要:
      目的 观察成人型神经元核内包涵体病(NⅡD)MRI表现。方法 回顾性分析5例成人型NⅡD,观察病变位置、形态、信号特点及进展情况。结果 5例NⅡD均有不同程度大脑半球萎缩、侧脑室扩张及Fazekas 2级及以上脑白质病变,弥散加权成像(DWI)可见双侧大脑额叶皮髓质交界区对称性曲线样高信号,表观弥散系数(ADC)图呈低信号;液体衰减反转恢复(FLAIR)序列T2WI中,2例分别于小脑蚓部旁、小脑中脚见对称性片状高信号。治疗后, 1例DWI示双侧大脑额叶皮髓质交接区高信号扩展至双侧顶叶,1例FLAIR-T2WI示小脑蚓部旁高信号范围扩大。结论 DWI大脑额叶皮髓质交界区曲线样高信号为NⅡD的特征性MRI表现,有助于诊断。
英文摘要:
      Objective To observe MRI manifestations of adult-onset neuronal intranuclear inclusion disease (NⅡD). Methods Data of 5 patients with adult-onset NⅡD were retrospectively analyzed, and the location, morphology and signal characteristics of lesions and disease progression were observed.Results Different degrees of cerebral hemispheric atrophy were found in all 5 cases of NⅡD, accompanied by lateral ventricle dilation and white matter lesions of Fazekas grade 2 and above. Diffusion weighted imaging (DWI) showed symmetrically curvilinear hyperintense signals at the cortex-medulla junction of bilateral frontal lobes, which present as low signals in apparent diffusion coefficient (ADC) images. Fluid attenuated inversion recovery (FLAIR)-T2WI showed symmetrical patchy hyperintense signals in the cerebellar vermis and middle cerebellar peduncle in 2 cases, respectively. After treatment, DWI showed extension of hyperintense signals at the cortex-medulla junction of bilateral frontal lobes to bilateral parietal lobes in 1 case, while FLAIR-T2WI detected hyperintense signal near the cerebellar vermis enlarged in 1 case.Conclusion Curvilinear hyperintense signals at the cortex-medulla junction of bilateral frontal lobes on DWI was the characteristic MRI manifestation of NⅡD, which was helpful to diagnosis of NⅡD.
查看全文  查看/发表评论  下载PDF阅读器