| 张楚君,刘朝奇,赵云.超声靶向微泡破坏用于肝脏疾病研究进展[J].中国介入影像与治疗学,2024,21(11):708-711 |
| 超声靶向微泡破坏用于肝脏疾病研究进展 |
| Research progresses of ultrasound targeted microbubbles destruction in liver diseases |
| 投稿时间：2024-05-14 修订日期：2024-06-26 |
| DOI：10.13929/j.issn.1672-8475.2024.11.012 |
| 中文关键词: 肝 微泡 分子靶向治疗 超声检查 |
| 英文关键词:liver microbubbles molecular targeted therapy ultrasonography |
| 基金项目:湖北省自然科学基金计划项目（2023AFB137）。 |
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| 中文摘要: |
| 肝脏疾病发病率高，现有治疗手段周期长、不良反应多、复发风险高，尤其慢性肝病可进展为终末期肝硬化或肝癌；临床亟待开发新型诊疗方法。超声靶向微泡破坏（UTMD）利用超声辐照触发定点释放微泡内药物与外源基因，用于诊疗肝脏疾病前景广阔。本文就UTMD诊疗肝脏疾病研究进展进行综述。 |
| 英文摘要: |
| The incidence of liver diseases remain high， which have long cycle， many adverse reactions and high recurrence risks under the existing treatments， especially chronic liver disease might develop to end-stage cirrhosis or liver cancer. New diagnosis and treatment methods for liver diseases are urgent needed in clinical practice. Ultrasound targeted microbubbles destruction （UTMD） trigger targeted release of drugs and foreign genes in microbubbles using ultrasound irradiation， having broad application prospect for diagnosing and treating liver diseases. The research progresses of UTMD in liver diseases were reviewed in this article. |
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