褚立梅,王涛,袁静静.CT引导下背根神经节脉冲射频联合连续射频治疗胸段带状疱疹后神经痛:有效性与安全性[J].中国介入影像与治疗学,2025,22(4):247-250
CT引导下背根神经节脉冲射频联合连续射频治疗胸段带状疱疹后神经痛:有效性与安全性
CT-guided dorsal root ganglion pulsed radiofrequency combined with continuous radiofrequency for thoracic postherpetic neuralgia: Efficacy and safety
投稿时间:2024-11-05  修订日期:2025-01-21
DOI:10.13929/j.issn.1672-8475.2025.04.004
中文关键词:  神经痛,带状疱疹后  神经节,脊  射频消融  体层摄影术,X线计算机
英文关键词:neuralgia, postherpetic  ganglia, spinal  radiofrequency ablation  tomography, X-ray computed
基金项目:
作者单位E-mail
褚立梅 河南中医药大学第五临床医学院(郑州人民医院)麻醉科, 河南 郑州 450003 lilll111@126.com 
王涛 郑州大学第三附属医院麻醉科, 河南 郑州 450052  
袁静静 郑州大学第一附属医院麻醉科, 河南 郑州 450052  
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中文摘要:
      目的 观察CT引导下背根神经节脉冲射频联合连续射频治疗胸段带状疱疹后神经痛(PHN)的有效性及安全性。方法 回顾性纳入110例胸段PHN并均分为观察组(脉冲射频联合连续射频治疗)与对照组(单纯脉冲射频治疗);对比2组治疗前及治疗后1天、7天、1个月及3个月视觉模拟评分法(VAS)疼痛度评分,以及治疗有效率及不良反应发生率。结果 治疗前2组VAS疼痛度评分差异无统计学意义(P=0.818);治疗后1天、7天、1个月及3个月,观察组VAS疼痛度评分均低于对照组(P均<0.001)。观察组治疗有效率高于对照组[98.18%(54/55) vs. 85.45%(47/55),P=0.025]而不良反应发生率低于对照组[1.82%(1/55) vs. 12.73%(7/55),P=0.028]。结论 CT引导下背根神经节脉冲射频结合连续射频可显著减轻胸段PHN疼痛程度、减少不良反应。
英文摘要:
      Objective To observe the efficacy and safety of CT-guided pulsed radiofrequency combined with continuous radiofrequency treatment for thoracic postherpetic neuralgia (PHN). Methods A total of 110 patients with thoracic PHN were retrospectively enrolled and divided into observation group (pulsed radiofrequency combined with continuous radiofrequency treatment) and control group (pulsed radiofrequency treatment) (each n=55). The visual analogue scale (VAS) pain scores before and 1 day, 7 days, 1 month and 3 months after treatment, also the treatment effective rate and incidence of adverse reactions were compared between groups. Results No significant difference of VAS pain scores was found between groups before treatment (P=0.818), while 1 day, 7 days, 1 month and 3 months after treatment, observation group had lower VAS pain scores than control group (all P<0.001). The treatment effective rate in observation group was higher than that in control group (98.18% [54/55] vs. 85.45% [47/55], P=0.025), while the incidence of adverse reactions in observation group was lower than that in control group (1.82% [1/55] vs. 12.73% [7/55], P=0.028). Conclusion CT-guided pulsed radiofrequency combined with continuous radiofrequency could effectively reduce pain degree of thoracic PHN and adverse reactions.
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