| 王丽佳,于明安,曹时亮,魏莹,赵朕龙,伍洁.基于常规超声及超声造影表现分析热消融治疗后甲状腺良性结节体积缩小率的影响因素[J].中国介入影像与治疗学,2025,22(5):319-323 |
| 基于常规超声及超声造影表现分析热消融治疗后甲状腺良性结节体积缩小率的影响因素 |
| Impact factors of volume reduction rate of benign thyroid nodules after thermal ablation based on manifestations of conventional ultrasound and contrast-enhanced ultrasound |
| 投稿时间：2025-03-10 修订日期：2025-04-25 |
| DOI：10.13929/j.issn.1672-8475.2025.05.004 |
| 中文关键词: 甲状腺结节 消融技术 超声检查 治疗转归 危险因素 |
| 英文关键词:thyroid nodule ablation techniques ultrasonography treatment outcome risk factors |
| 基金项目:中央高水平医院临床科研业务费专项（2024-NHLHCRF-PYI-04）、国家自然科学基金（62176268）、北京市研究型病房建设项目（2022-YJXBF-04-04）、中央高水平医院临床科研业务费专项（2023-NHLHCRF-YYPP-TS-01）。 |
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| 中文摘要: |
| 目的 基于常规超声及超声造影（CEUS）表现分析热消融治疗后甲状腺良性结节体积缩小率（VRR）的影响因素。方法 回顾性分析238例接受热消融治疗的甲状腺良性结节，根据治疗后12个月病灶VRR将其分为VRR＜75%组（n=93）及VRR≥75%组（n=145）；采用多因素logistic回归分析基于常规超声及CEUS表现筛选热消融治疗后12个月甲状腺良性结节VRR的独立影响因素；绘制受试者工作特征曲线，计算曲线下面积（AUC），评估联合上述各因素预测病灶VRR的效能。结果 高回声、钙化、囊实性成分、高增强、增强缺损及高消融能量均为热消融治疗12个月后甲状腺良性结节VRR的独立危险因素，而环状增强为其独立保护因素（P均＜0.05）；联合上述因素预测热消融治疗12个月后甲状腺良性结节VRR的AUC为0.926。结论 高回声、钙化、囊实性成分、高增强、增强缺损及高消融能量为热消融治疗12个月后甲状腺良性结节VRR的独立危险因素，环状增强为其独立保护因素。 |
| 英文摘要: |
| Objective To explore the impact factors of volume reduction rate （VRR） of benign thyroid nodules after thermal ablation based on conventional ultrasound and contrast-enhanced ultrasound （CEUS） manifestations. Methods Totally 238 patients with benign thyroid nodules who underwent thermal ablation were retrospectively enrolled and divided into VRR＜75% group （n=93） and VRR≥75% group （n=145） according to VRR of lesions 12 months after treatment. Multivariate logistic regression analysis was used to screen the independent impact factors of VRR of lesions 12 months after thermal ablation based on conventional ultrasound and CEUS manifestations. Receiver operating characteristic curve was plotted， the area under the curve （AUC） was calculated to evaluate the efficacy of the combination of the above factors for predicting VRR of lesions. Results High echo， calcification， cystic and solid components， high enhancement， enhancement loss and high ablation energy were all independent risk factors， while circular enhancement was the independent protective factor of VRR of benign thyroid nodules 12 months after thermal ablation （all P＜0.05）. The AUC of combination of the above factors for predicting VRR of benign thyroid nodules 12 months after thermal ablation was 0.926. Conclusion High echo， calcification， cystic and solid components， high enhancement， enhancement loss and high ablation energy were all independent risk factors， while circular enhancement was the independent protective factor of VRR of benign thyroid nodules 12 months after thermal ablation. |
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