| 徐丹凤,王志利,孙丽妍,闫凤琴.青春期异常子宫出血所致超声参数改变[J].中国介入影像与治疗学,2025,22(12):791-795 |
| 青春期异常子宫出血所致超声参数改变 |
| Changes of ultrasonic parameters caused by adolescent abnormal uterine bleeding |
| 投稿时间：2025-08-18 修订日期：2025-11-02 |
| DOI：10.13929/j.issn.1672-8475.2025.12.008 |
| 中文关键词: 青少年 子宫不规则出血 超声检查 前瞻性研究 |
| 英文关键词:adolescent metrorrhagia ultrasonography prospective studies |
| 基金项目:河北省医学科学研究课题计划（20251602）。 |
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| 中文摘要: |
| 目的 观察青春期异常子宫出血（AUB）所致超声参数改变。方法 前瞻性纳入200例女性青春期患者，根据有无AUB分为观察组（n=100）与对照组（n=100）。以经腹部超声测量子宫体积、子宫内膜厚度、卵巢体积及子宫螺旋动脉和卵巢间质动脉血流动力学参数［包括收缩期峰值流速（PSV）、阻力指数（RI）和收缩末期峰值与舒张末期峰值比值（S/D）］并进行组间比较；采用多因素logistic回归筛选青春期AUB的独立危险因素，以Pearson相关分析观察超声参数与AUB的相关性。结果 观察组子宫体积、子宫内膜厚度、子宫螺旋动脉RI及S/D、卵巢间质动脉RI及S/D均大于，而子宫螺旋动脉及卵巢间质动脉PSV均小于对照组（P均＜0.05）。子宫体积增大、子宫内膜增厚、子宫螺旋动脉PSV降低、子宫螺旋动脉RI升高及卵巢间质动脉PSV降低均为青春期AUB的独立危险因素（P均＜0.05）。子宫体积、子宫内膜厚度及子宫螺旋动脉RI增大均与青春期AUB呈弱-低度正相关（r=0.312、0.274、0.341，P均＜0.05），子宫螺旋动脉PSV增大与之呈低度负相关（r=－0.386，P＜0.01）。结论 青春期AUB可致子宫体积增大、子宫内膜增厚及子宫螺旋动脉和卵巢间质动脉血流动力学异常。 |
| 英文摘要: |
| Objective To observe the changes of ultrasonic parameters caused by adolescent abnormal uterine bleeding （AUB）. Methods A total of 200 female adolescent patients were prospectively enrolled and divided into observation and control group （each n=100） according to the presence or absence of AUB. Transabdominal ultrasonography was performed to measure uterine volume， endometrial thickness， ovarian volume， as well as hemodynamic parameters of uterine spiral artery and ovarian stromal artery， including peak systolic velocity （PSV）， resistance index （RI） and systolic/diastolic ratio （S/D） and compared between groups. Multivariate logistic regression was used to identify independent risk factors associated with adolescent AUB. Pearson correlation analysis was performed to assess the relationships of ultrasonic parameters and AUB. Results Uterine volume， endometrial thickness， RI and S/D of uterine spiral artery， RI and S/D of ovarian stromal artery in observation group were all higher， while PSV of both uterine spiral artery and ovarian stromal artery in observation group were both lower than those in control group （all P＜0.05）. Increased uterine volume， increased endometrial thickness， decreased uterine spiral artery PSV， increased uterine spiral artery RI and decreased ovarian stromal artery PSV were all independent risk factors associated with adolescent AUB （all P＜0.05）. Increased uterine volume， endometrial thickness and uterine spiral artery RI were all weakly to mildly positively correlated （r=0.312， 0.274， 0.341， all P＜0.05）， whereas increased uterine spiral artery PSV showed mild negative correlation with adolescent AUB （r=－0.386， P＜0.01）. Conclusion Adolescent AUB might bring increased uterine volume， thickened endometrial and abnormal hemodynamic changes of uterine spiral arteries and ovarian stromal arteries. |
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