| 程彬,韩雪,顾国晓,张菲菲,刘英彦.弥散张量成像参数用于预测面肌痉挛经神经内镜微血管减压治疗后延迟痊愈[J].中国介入影像与治疗学,2026,23(7):394-398 |
| 弥散张量成像参数用于预测面肌痉挛经神经内镜微血管减压治疗后延迟痊愈 |
| Diffusion tensor imaging parameters for predicting delayed cure after neuroendoscopic microvascular decompression for hemifacial spasm |
| 投稿时间：2026-03-11 修订日期：2026-06-17 |
| DOI：10.13929/j.issn.1672-8475.2026.07.003 |
| 中文关键词: 偏侧面肌痉挛 磁共振成像 神经外科手术 |
| 英文关键词:hemifacial spasm magnetic resonance imaging neurosurgical procedures |
| 基金项目:邢台市重点研发计划（2023ZC121）。 |
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| 摘要点击次数: 44 |
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| 中文摘要: |
| 目的 观察弥散张量成像（DTI）参数用于预测面肌痉挛经神经内镜微血管减压治疗后延迟痊愈的价值。方法 前瞻性纳入122例偏侧面肌痉挛患者，根据神经内镜微血管减压治疗后当日症状是否完全消失分为立即治愈组（n=78）与延迟痊愈组（n=44）；将临床资料及DTI参数［包括各向异性分数（FA）及表观弥散系数（ADC）］纳入多因素logistic回归分析，筛选面肌痉挛经神经内镜微血管减压治疗后延迟痊愈的独立影响因素；绘制受试者工作特征曲线，计算曲线下面积（AUC），评估DTI参数的预测效能。结果 病程、使用卡马西平＞6个月、使用肉毒毒素、痉挛程度、患侧ADC及患侧FA均为面肌痉挛经神经内镜微血管减压治疗后延迟痊愈的独立影响因素（P均＜0.05）；基于患侧ADC、患侧FA及二者联合预测延迟治愈的AUC分别为0.776、0.779及0.821，联合预测效能高于各单一参数（P均＜0.05）。结论 DTIFA及ADC用于联合预测面肌痉挛经神经内镜微血管减压治疗后延迟痊愈效能良好。 |
| 英文摘要: |
| Objective To observe the value of diffusion tensor imaging （DTI） parameters for predicting delayed cure of hemifacial spasm after neuroendoscopic microvascular decompression. Methods Totally 122 patients with unilateral hemifacial spasm were prospectively enrolled and divided into immediate cure group （n=78） and delayed cure group （n=44） according to whether symptoms completely disappeared on the day after neuroendoscopic microvascular decompression. Clinical data and DTI parameters， including fractional anisotropy （FA） and apparent diffusion coefficient （ADC）， were incorporated in multivariate logistic regression analysis to screen independent impact factors for delayed cure of hemifacial spasm after neuroendoscopic microvascular decompression. Then receiver operating characteristic curves were drawn， and the area under the curve （AUC） was calculated to evaluate the efficacy of DTI parameters. Results Disease duration， administration of carbamazepine＞6 months， botulinum toxin application， disease severity， ipsilateral ADC and ipsilateral FA were all independent impact factors of delayed cure of hemifacial spasm after neuroendoscopic microvascular decompression （all P＜0.05）. AUC of ipsilateral ADC， ipsilateral FA and their combination for predicting delayed cure was 0.776， 0.779 and 0.821， respectively. The efficacy of combination of ipsilateral ADC and ipsilateral FA was better than each parameter alone （all P＜0.05）. Conclusion Combination of DTI derived FA and ADC exhibited good efficacy for predicting delayed cure of hemifacial spasm after neuroendoscopic microvascular decompression. |
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