| 俞晓,徐亮,冯晔,翟建,俞咏梅.双能CT诊断膝关节痛风性关节炎伴膝骨关节炎[J].中国医学影像技术,2025,41(5):788~793 |
| 双能CT诊断膝关节痛风性关节炎伴膝骨关节炎 |
| Dual-energy CT for diagnosing knee gouty arthritis complicated with knee osteoarthritis |
| 投稿时间：2024-11-12 修订日期：2025-02-13 |
| DOI：10.13929/j.issn.1003-3289.2025.05.020 |
| 中文关键词: 关节炎,痛风性 骨关节炎,膝 骨髓水肿 体层摄影术,X线计算机 |
| 英文关键词:arthritis, gouty osteoarthritis, knee bone marrow edema tomography, X-ray computed |
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| 中文摘要: |
| 目的 观察双能CT(DECT)诊断膝关节痛风性关节炎(GA)伴膝骨关节炎(KOA)的价值。方法 回顾性纳入48例膝关节GA(GA组)、30例KOA(KOA组)及60例膝关节GA伴KOA(GA+KOA组);比较3组间及两两组间临床及影像学资料,分析DECT诊断膝关节GA伴KOA的效能。结果 3组间及两两组间骨髓水肿(BME)检出率及其CT值差异均有统计学意义(P均＜0.05)。GA组与GA+KOA组病程、血清尿酸(SUA)、单钠尿酸盐(MSU)体积、骨侵蚀评分及CT值差异均有统计学意义(P均＜0.05);其中,以骨侵蚀评分及CT值诊断膝关节GA伴KOA的曲线下面积(AUC)分别为0.779及0.824,联合上述5项诊断的AUC为0.898,高于单一各参数(P均＜0.05)。结论 DECT有助于诊断膝关节GA伴KOA;联合临床参数可进一步提高其诊断效能。 |
| 英文摘要: |
| Objective To observe the value of dual-energy CT (DECT) for diagnosing knee gouty arthritis (GA) complicated with knee osteoarthritis (KOA). Methods Forty-eight cases of GA (GA group), 30 cases of KOA (KOA group) and 60 cases of GA complicated with KOA (GA+KOA group) were retrospectively enrolled. Clinical and imaging data were compared among 3 groups and between each 2 groups, and the efficacy of DECT for diagnosing knee GA complicated with KOA was analyzed. Results Significant differences of detection rate and CT value of bone marrow edema (BME) were found among 3 groups and between each 2 groups (all P＜0.05), also of the course of disease, serum uric acid (SUA), monosodium urate (MSU) volume, bone erosion score and CT value between GA group and GA+KOA group (all P＜0.05). The area under the curve (AUC) of bone erosion score and CT value for diagnosing knee GA complicated with KOA was 0.779 and 0.824, respectively, and of the combination of the above 5 indexes was 0.898, higher than that of each parameter alone (all P＜0.05). Conclusion DECT was helpful for diagnosing knee GA complicated with KOA, and further combining with clinical parameters could improve its diagnostic efficacy. |
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