| 李慧瑶,张宁,岳云龙.MR mDixon-Quant序列用于鉴别乳糜性与非乳糜性胸腔积液[J].中国医学影像技术,2025,41(9):1522~1525 |
| MR mDixon-Quant序列用于鉴别乳糜性与非乳糜性胸腔积液 |
| MR mDixon-Quant sequence for differentiating chylous and non-chylous pleural effusion |
| 投稿时间：2024-12-20 修订日期：2025-08-12 |
| DOI：10.13929/j.issn.1003-3289.2025.09.014 |
| 中文关键词: 乳糜胸|磁共振成像|脂肪分数 |
| 英文关键词:chylothorax|magnetic resonance imaging|fat fraction |
| 基金项目:国家自然科学基金(61876216)。 |
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| 中文摘要: |
| 目的 观察基于MR mDixon-Quant序列鉴别乳糜性与非乳糜性胸腔积液的价值。方法 回顾性分析28例乳糜性胸腔积液(乳糜组)及18例非乳糜性胸腔积液(非乳糜组)mDixon-Quant数据;基于脂肪分数(FF)图测量胸腔积液平均FF值及胸腔积液脂质成分聚集区平均FF值;以Pearson相关分析评估实验室指标与FF值的相关性;绘制受试者工作特征曲线,计算曲线下面积(AUC),比较2种方法所测FF值鉴别乳糜性与非乳糜性胸腔积液的效能。结果 胸腔积液的平均FF值与甘油三酯、总胆固醇及白蛋白水平分别呈中度、中度及低度正相关(r=0.727、0.661、0.445,P均＜0.01);以0.95%为最佳截断值,其鉴别乳糜性与非乳糜性胸腔积液的敏感度、特异度及AUC分别为85.71%、100%及0.962。胸腔积液脂质成分聚集区的平均FF值与甘油三酯、总胆固醇及白蛋白水平分别呈高度、中度及低度正相关(r=0.815、0.739、0.492,P均＜0.01);以0.87%为最佳截断值,其鉴别乳糜性与非乳糜性胸腔积液的敏感度、特异度及AUC分别为92.86%、100%及0.982。上述2种方法鉴别效能差异无统计学意义(P=0.203)。结论 基于MR mDixon-Quant序列可无创鉴别乳糜性与非乳糜性胸腔积液;测量脂质成分聚集区的平均FF值能更准确地反映胸腔积液脂肪成分。 |
| 英文摘要: |
| Objective To observe the value of MR mDixon-Quant sequence for differentiating chylous and non-chylous pleural effusions. Methods MR mDixon-Quant sequence data of 28 cases of chylous pleural effusion (chylous group) and 18 cases of non-chylous pleural effusion (non-chylous group) were retrospectively analyzed. The average fat fraction (FF) value of pleural effusion and the average FF value of lipid component aggregation area within pleural effusion were measured based on FF maps, respectively. Pearson correlation analysis was used to evaluate the relationships of laboratory indicators and FF values. Receiver operating characteristic curve was plotted, and the area under the curve (AUC) was calculated to evaluate the diagnostic efficacy of FF values measured using the above 2 methods for distinguishing chylous and non-chylous pleural effusions. Results The average FF value of pleural effusion showed moderate or weak positive correlations with triglyceride, total cholesterol and albumin (r=0.727, 0.661, 0.445, all P＜0.01). Taken 0.95% as the optimal cutoff value, the sensitivity, specificity and AUC of the average FF value of pleural effusion for distinguishing chylous from non-chylous pleural effusions was 85.71%, 100% and 0.962, respectively. The average FF value of lipid component aggregation area in pleural effusion exhibited strong, moderate and weak positive correlations with triglyceride, total cholesterol and albumin, respectively (r=0.815, 0.739, 0.492, all P＜0.01). Taken 0.87% as the optimal cutoff value, the sensitivity, specificity and AUC of the average FF value of lipid component aggregation area in pleural effusion for distinguishing chylous from non-chylous pleural effusions was 92.86%, 100% and 0.982, respectively. No significant difference of diagnostic performance was found between these 2 methods (P=0.203). Conclusion MR mDixon-Quant sequence enabled non-invasive discrimination of chylous and non-chylous pleural effusions. The average FF value of lipid component aggregation area could more accurately reflect the fat component of pleural effusion. |
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