| 颜晓一,桂阳,邵禹铭,姜玉新,吕珂.功能和定量影像学评估及预测新辅助治疗用于胰腺癌效果研究进展[J].中国医学影像技术,2025,41(9):1591~1594 |
| 功能和定量影像学评估及预测新辅助治疗用于胰腺癌效果研究进展 |
| Research progresses in functional and quantitative imaging for evaluating and predicting efficacy of neoadjuvant therapy of pancreatic cancer |
| 投稿时间：2024-11-25 修订日期：2025-04-02 |
| DOI：10.13929/j.issn.1003-3289.2025.09.029 |
| 中文关键词: 胰腺肿瘤|新辅助治疗|多模态显像 |
| 英文关键词:pancreatic neoplasms|neoadjuvant therapy|multimodal imaging |
| 基金项目:国家自然科学基金(82171968)、北京协和医院中央高水平医院临床科研专项(2022-PUMCH-B-065、2022-PUMCH-D-001)、中国医学科学院医学与健康科技创新工程项目(2023-I2M-C&T-A-005)。 |
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| 中文摘要: |
| 胰腺癌起病隐匿、预后差,根治性切除为主要治疗方式。新辅助治疗可提高切除胰腺癌边缘阴性率、延长患者生存期。功能及定量影像学可无创反映与化学治疗耐药性密切相关的肿瘤微环境特征,为评估及预测新辅助治疗用于胰腺癌的效果提供了新视角。本文就功能及定量影像学在评估及预测新辅助治疗用于胰腺癌效果研究进展进行综述。 |
| 英文摘要: |
| Pancreatic cancer has a concealed onset and poor prognosis, and surgical resection is the main treatment method. Neoadjuvant therapy may improve the rate of negative resection margin and prolong overall survival of patients with pancreatic cancer. Functional and quantitative imaging can non-invasively reflect tumor microenvironment characteristics related to chemotherapy resistance, providing a new perspective for evaluating and predicting the efficacy of neoadjuvant therapy for pancreatic cancer. The research progresses in functional and quantitative imaging for evaluating and predicting the efficacy of neoadjuvant therapy of pancreatic cancer were reviewed in this article. |
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