| 何小溪,陈涓.多模态影像用于超常规时间窗缺血性脑卒中研究进展[J].中国医学影像技术,2025,41(9):1604~1607 |
| 多模态影像用于超常规时间窗缺血性脑卒中研究进展 |
| Research progresses in application of multimodal imaging in ischemic stroke beyond conventional time window |
| 投稿时间：2025-06-15 修订日期：2025-09-10 |
| DOI：10.13929/j.issn.1003-3289.2025.09.032 |
| 中文关键词: 缺血性脑卒中|治疗时间|多模态成像 |
| 英文关键词:ischemic stroke|time-to-treatment|multimodal imaging |
| 基金项目:北京医院临床研究"助航"专项(BJ-2023-076)、北京医院"国家自然科学基金预研专项"(BJ-2020-131)。 |
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| 中文摘要: |
| 缺血性脑卒中(IS)是最常见脑卒中类型。治疗急性缺血性脑卒中(AIS)高度依赖时间窗,但脑组织对缺血的耐受程度存在个体异质性,部分患者仍可获益于超出常规时间窗的治疗。利用多模态影像评估核心梗死区与缺血半暗带可实现"组织窗"指导下的个体化治疗决策,拓展超常规时间窗治疗机会。本文围绕多模态影像学用于筛选可获益于超常规时间窗AIS患者、治疗决策及评估预后的价值,以及其面临挑战和发展方向进行综述。 |
| 英文摘要: |
| Ischemic stroke (IS) is the most common type of stroke, and the treatment of acute ischemic stroke (AIS) is highly time-dependent. There is considerable individual heterogeneity in the tolerance of brain tissues to ischemia, and some patients may still be benefitted from treatment beyond conventional time window. The application of multimodal imaging in evaluating the core infarct area and ischemic penumbra enabled individualized treatment decisions guided by "tissue window", hence significantly expanded treatment opportunities for patients beyond conventional time window. The application value of multimodal imaging in screening ones able to be benefitted from treatment beyond conventional time window, treatment decision-making and predicting prognosis of AIS patients beyond conventional time window, as well as the challenges and future directions of multimodal imaging in this field were reviewed in this article. |
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