何晓峰,李彦豪,陈汉威,卢伟,陈勇,曾庆乐,赵剑波,许小丽,彭静,申鹏.臭氧治疗腰椎间盘突出症600例临床疗效分析[J].中国介入影像与治疗学,2005,2(5):338-341
臭氧治疗腰椎间盘突出症600例临床疗效分析
Intradiscal injection of O2-O3 to treat lumbar disc herniations: clinical therapeutic effect analysis with 600 cases
投稿时间:2005-06-02  修订日期:2005-07-04
DOI:
中文关键词:  椎间盘移位  椎间盘化学松解术  臭氧  
英文关键词:Intervertebral disk displacement  Intervertebral disk chemolysis  Ozone  Oxygen
基金项目:
作者单位
何晓峰 南方医科大学南方医院介入治疗科,广东广州 510515 
李彦豪 南方医科大学南方医院介入治疗科,广东广州 510515 
陈汉威 番禺区人民医院放射科,广东广州 511400 
卢伟 南方医科大学南方医院介入治疗科,广东广州 510515 
陈勇 南方医科大学南方医院介入治疗科,广东广州 510515 
曾庆乐 南方医科大学南方医院介入治疗科,广东广州 510515 
赵剑波 南方医科大学南方医院介入治疗科,广东广州 510515 
许小丽 南方医科大学南方医院介入治疗科,广东广州 510515 
彭静 广州市番禺区何贤纪念医院肿瘤科,广东广州 511400 
申鹏 南方医科大学南方医院介入治疗科,广东广州 510515 
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中文摘要:
      目的 探讨臭氧椎间盘注射术对腰椎间盘突出症的疗效。方法 600例患者经CT 或MR检查证实为腰椎间盘突出症,主要表现为腰背痛及下肢麻痛。其中椎间盘膨出234例,突出361例,脱垂5例。在透视监视下采用21 G穿刺针经皮穿刺至腰椎间盘,实施盘内及椎旁间隙臭氧注射术。盘内注射3~5 ml,椎旁间隙注射10~15 ml,O3 浓度为30~50 μg/ml。结果 随访6~54个月,总有效率为80.2%。显效409例(68.2%),有效72例(12%),无效119例(19.8%),无任何严重并发症发生。结论 经皮穿刺O2-O3 混合气体注射术是治疗腰椎间盘突出症的一种安全、有效的方法。
英文摘要:
      Objective To evaluate the therapeutic effect for the treatment of lumbar disc herniation using injection of intradiscal and paraspinal space with O2-O3 mixture. Methods Six hundred patients were selected in present study. Most of patients presented the symptoms of sciatica and low back pain. The diagnosis of the lumbar disc herniation including 234 buldging, 361 protrusion and 5 extrusion was verified by CT or MR imaging. O2-O3 mixture at 30-40 μg/ml and 21 G puncture needles were prepared. The injection was conducted through the puncture of intradiscal and paraspinal space. For each herniated disc treatment, 3-5 ml O2-O3 mixture was injected into intradiscal space and 10-15 ml into paraspinal space. Results The patients were followed up from 6 to 54 months after treatment. The therapeutic effect showed that 409 patients (68.2%) had excellent recovery, and 72 cases (12%) had significant relief of symptoms, and 119 patients (19.8%) got failure in treatment. No any serious complication occurred. Conclusion The therapeutic method developed by using O2-O3 mixture injection in lumbar intradiscal and paraspinal space was a safe and effective method for the treatment of the lumbar disc herniation.
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